有机酸催化合成2,4,6,8,10,12-六苄基-2,4,6,8,10,12-六氮杂异伍兹烷  

Preparation of 2,4,6,8,10,12-Hexabenzyl-2,4,6,8,10,12-hexaazaisowurtzitane Catalyzed by Organic Acids

作　　者：郑福平[1] 欧育湘[1] 陈江涛[1] 陈博仁[1] 周智明[1] 叶玲[2] 赵道慧 

机构地区：[1]北京理工大学化工与材料学院,北京100081 [2]首都医科大学基础医学院,北京100054 [3]北京轻工业学院化工系,北京100037

出　　处：《精细化工》2000年第1期27-29,共3页Fine Chemicals

基　　金：国防科工委预研基金!12060451867

摘　　要：研究了十几种有机酸对合成２，４，６，８，１０，１２六苄基２，４，６，８，１０，１２六氮杂异伍兹烷（Ⅰ）的催化作用，每种催化剂均取得了较好催化效果。尤其是水杨酸和对甲苯磺酸，可分别使化合物Ⅰ的产率达到７５％ 和８２％ ～８４％ 。随对甲苯磺酸用量的增大，化合物Ⅰ的产率先增大后减小。To study the catalytic effect of organic acids on the preparation of 2,4,6,8,10,12 hexabenzyl 2,4,6,8,10,12 hexaazaisowurtzitane(Ⅰ) more than ten kinds of organic acids were tested. Every organic acid used showed good performance in the preparation of compound Ⅰ. The yields of compound Ⅰ reached 75% and 82%～84% respectively when using salicylic acid and p toluenesulfonic acid as catalysts. The yield of compound Ⅰ increased first and then decreased with increase of the amount of p toluenesulfonic acid.

关 键 词：醛胺缩合 催化剂 六氮杂异伍兹烷 有机酸 催化 

分 类 号：TQ253.29[化学工程—有机化工]