冰岛参对小鼠肠道粘膜SIgA分泌的影响  

Promotion effect of Cucumaria frondosa on the secretion of mice intestinal SIgA

作　　者：左涛[1] 律迎春[1] 曹露[1] 唐庆娟[1] 王静凤[1] 薛长湖[1] 张彩欣[2] 

机构地区：[1]中国海洋大学食品科学与工程学院,山东青岛266003 [2]青岛市市立医院病理科,山东青岛266003

出　　处：《食品工业科技》2012年第1期373-375,共3页Science and Technology of Food Industry

基　　金：海洋公益性行业科研专项(201105029);国家自然科学基金(31071525)

摘　　要：目的:探讨冰岛参(Cucumaria frondosa)对小鼠肠道粘膜SIgA分泌的影响。方法:将50只Balb/c小鼠随机分为5组:正常组、模型组、低剂量组、中剂量组、高剂量组。采用环磷酰胺诱导免疫低下模型,取小鼠肠道进行组织学观察、检测肠粘膜SIgA的含量,观察冰岛参对肠道粘膜免疫的保护作用。结果:与模型组相比,低剂量冰岛参摄入能促进肠粘膜SIgA的分泌,对小肠绒毛有一定的保护作用。结论:低剂量冰岛参摄入量能够明显保护小鼠肠粘膜,促进SIgA的分泌,对肠炎有一定的防治作用。Purpose：Investigate the effect of Cucumaria frondosa on the secretion of mice intestinal SIgA.Methods：Fifty mice were randomly divided into 5 groups：normal group,model group,low dose group,medium dose group,high dose group.Used models of low-immunity mice induced by injected cyclophosphamide,detect SIgA content and histological observation of ileum.Results：Compared with model group,low dose Cucumaria frondosa could have remarkable effect of protecting intestinal villi,and the amount of SIgA secretion.Conclusions：Cucumaria frondosa can enhance the amount of intestinal SIgA,and thus protect intestinal villi from hurting,which makes it a good material to prevent enteritis.

关 键 词：冰岛参 体重 小肠绒毛 SIGA BALB/C小鼠 

分 类 号：TS201.4[轻工技术与工程—食品科学]