Alum （KAI（SO4）2·12H2O） Catalyzed Multicomponent Transformation： Simple, Efficient, and Green Route to Synthesis of Functional- ized Spiro[chromeno[2,3-d]pyrimidine-5,3＇-indoline]-tetraones in Ionic Liquid Media  

作　　者：Mirhosseini Moghaddam, Mojtaba Bazgir, Ayoob Mohammad Mehdi, Akhondi Ghahremanzadeh, Ramin 

机构地区：[1]Nanobiotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran [2]Department of Chemistry, Shahid Beheshti University, Tehran, Iran [3]Reproductive Research Center, Avicenna Research Institute, ACECR, Tehran, Iran

出　　处：《Chinese Journal of Chemistry》2012年第3期709-714,共6页中国化学（英文版）

摘　　要：The combination of isatin, barbituric acid, and cyclohexane-1,3-dione derivatives in the presence of alum （KAI（SO4）2· 12H2O） as a catalyst for 15 min was found to be a suitable and efficient method for the synthesis of spiro[chromeno[2,3-d]pyrimidine-5,3＇-indoline]-tetraones.The combination of isatin, barbituric acid, and cyclohexane-1,3-dione derivatives in the presence of alum （KAI（SO4）2· 12H2O） as a catalyst for 15 min was found to be a suitable and efficient method for the synthesis of spiro[chromeno[2,3-d]pyrimidine-5,3＇-indoline]-tetraones.

关 键 词：ISATIN SPIROOXINDOLES DIMEDONE barbituric acid ionic liquids 

分 类 号：O643.36[理学—物理化学] O626[理学—化学]