SPIROOXINDOLES

作品数：11被引量：7H指数：1
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相关领域：理学更多>>
相关机构：扬州大学更多>>
相关期刊：《Chinese Journal of Chemistry》《Organic Chemistry Frontiers》《Green Synthesis and Catalysis》《Chinese Chemical Letters》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Modular Assembly of Six-Membered Carbocyclic Spirooxindoles via Peterson Olefination/Michael Addition/C(sp^(3))Arylation Cascade
《Chinese Journal of Chemistry》2024年第21期2614-2620,共7页Feng-Cheng Jia Zi-Yi Yuan Na Luo Shuang-Xi Gu Xiao-Qiang Hu 
financial support of National Natural Science Foundation of China(21901193,22271314 and 22377097);the innovation foundation of Key Laboratory of Green Chemical Engineering Process of Ministry of Education(GCX2023002).
Concise assembly of spirooxindoles is of great significance but a challenging task in modern organic synthesis.Described herein is an unusual base-promoted[4+2]spiroannulation of rarely used isatin-derivedβ-silylcarb...
关键词：Cascade reaction SPIROOXINDOLE Peterson olefination C(sp^(3))arylation of oxindole Transition-metal-free 
Spirooxindoles:Recent report of green synthesis approach
《Green Synthesis and Catalysis》2024年第1期1-13,共13页Agus Rimus Liandi Antonius Herry Cahyana Diva Naufal Alfariza Rahma Nuraini Renita Wulan Sari Tio Putra Wendari 
The authors gratefully acknowledge financial support from the Universitas Islam Negeri Syarif Hidayatullah Jakarta through the grant of BOPTN 2023[Contract number:UN.01/KPA/189/2023].
Spirooxindole is a compound with a unique framework and broad bioactivities in medicine.In this study,we have reviewed various approaches or methods in synthesizing spirooxindole derivatives focused on green synthesis...
关键词：SPIROOXINDOLES Green synthesis CATALYSIS NANOPARTICLE Ultrasonic irradiation 
Synthesis of functionalized 3,2’-pyrrolidinyl spirooxindoles via domino 1,6-addition/annulation reactions of para-quinone methides and 3-chlorooxindoles
《Organic Chemistry Frontiers》2022年第3期615-626,共12页Xiaochen Tian Yongxing Zhang Weiwu Ren Yang Wang 
We are thankful for financial support from OUC,QNLM(LMDBCXRC201902,LMDBCXRC201903),tsqn201909056,tsqn202103152.The project is supported by the Fundamental Research Funds for the Central Universities.
A highly efficient base-mediated diastereoselective[4+1]cycloaddition of ortho-tosylaminophenyl-substituted p-QMs with 3-chlorooxindoles has been developed to afford 3,2’-pyrrolidinyl spirooxindoles in high yields wi...
关键词：DOMINO functional SPIRO 
NHC-catalysed retro-aldol/aldol cascade reaction enabling solvent-controlled stereodivergent synthesis of spirooxindoles被引量：1
《Chinese Chemical Letters》2021年第8期2567-2571,共5页Haijun Leng Qian Zhao Qing Mao Shuaijiang Liu Menglan Luo Rui Qin Wei Huang Gu Zhan 
financial support from Ministry of Science and Technology of China (No.2019ZX09721001-008);National Natural Science Foundation of China (Nos.81773890,22001024,82073997);the “Thousand Talents Program” of Sichuan Province and Xinglin Scholar Research Premotion Project of CDUTCM。
An N-heterocyclic carbene(NHC)-catalysed retro-aldol/aldol cascade reaction of spirooxindole-basedβ-hydroxyaldehyde has been developed.The ring opening-closure process enables the diastereodivergent synthesis of spir...
关键词：Asymmetric synthesis Solvent-controlled diastereodivergence Retro-aldol/aldol Cascade reaction SPIROOXINDOLE N-Heterocyclic carbene catalysis 
A highly efficient In(OTf)3-catalyzed[3+3]annulation of spirocyclopropyl oxindoles with 1,4-di-thiane-2,5-diol
《Chinese Chemical Letters》2020年第3期681-684,共4页Yongjia Hao Yi Gong Zhongyan Cao Ying Zhou Jian Zhou 
financial support from the National Natural Science Foundation of China(No.81660576);the Project of Guizhou Province Qian Ke He GZ[2015]4001;Guizhou Discipline Construction Project(No.GNYL[2017]008)。
Spirooxindoles play an important role in drug discove ry and development.The development of efficient methods for the synthesis of spirooxindoles from easily available sta rting materials is of curre nt interest Herei...
关键词：SPIROOXINDOLES Lewis acid catalysis [3+3]cycloaddition Sulfur HETEROCYCLES CYCLOPROPANE 
Stereoselective Construction of Complex Spirooxindoles via Bisthiourea Catalyzed Three-Component Reactions
《Chinese Journal of Chemistry》2018年第12期1182-1186,共5页Lin-Lin Zhang Ji-Wei Zhang Shao-Hua Xiang Zhen Guo Bin Tan 
the National Natural Science Foundation of China (Nos.21572095,21772081);Shenzhen Special Funds for the Development of Biomedicine, Internet,New Energy,and New Material Industries (JCW201S0430160022510).B.T.thanks the Thousand Young Talents Program for financial support.
[3＋3] Formal Cycloadditions of Nitrones from Isatins and Azaoxyallyl Cations for Construction of Spirooxindoles被引量：1
《Chinese Journal of Chemistry》2017年第6期857-860,共4页Weijia Lin Gu Zhan Minglin Shi Wei Du Yingchun Chen 
A [3＋3] formal cycloaddition reaction between in situ formed azaoxyallyl cations and nitrones from isatins has been developed, furnishing a spectrum of spiro[1,2,4-oxadiazinan-5-one]oxindoles in good to excellent yie...
关键词：CYCLOADDITION SPIROOXINDOLES azaoxyallyl cations NITRONES 1 3-dipoles 
Construction of polycyclic spirooxindoles through[3+2]annulations of Morita–Baylis–Hillman carbonates and 3-nitro-7-azaindoles被引量：1
《Chinese Chemical Letters》2017年第3期512-516,共5页Kai-Kai Wang Wei Du Jin Zhu Ying-Chun Chen 
financial support from the NSFC(21572135 and 21321061)
A mild and efficient dearomatic [3＋2] annulation reaction of 3-nitro-7-azaindoles and Morita Baylis Hillman carbonates from isatins was developed catalyzed by DMAP, affording the corresponding polycyclic spirooxindol...
关键词：Morita–Baylis–Hillman carbonates [3＋2] annulation Spirooxindoles Regioselectivity Dearomatization 
A cesium fluoride promoted efficient and rapid multicomponent synthesis of functionalized 2-amino-3-cyano-4H-pyran and spirooxindole derivatives被引量：3
《Chinese Chemical Letters》2015年第10期1273-1277,共5页Yogesh B.Wagh Yogesh A.Tayade Swapnil A.Padvi Bhupesh S.Patil Nilesh B.Patil Dipak S.Dalal 
SAIF Panjab University for providing analytical facilities for characterization of compounds
A rapid, one-pot and highly efficient protocol for the synthesis of pharmaceutically interesting functionalized 2-amino-3-cyano-4H-pyran and spirooxindole derivatives has been developed using commercially available Cs...
关键词：Cesium fluoride 2-Amino-3-cyano-4H-pyrans Spirooxindoles Rapid synthesis Multicomponent reactions 
AgF-Mediated Dialkylation of Activate Alkenes: An Efficient Access to Nitrile-Containing Spirooxindoles
《Chinese Journal of Chemistry》2014年第8期681-684,共4页Liang Wu Pinhong Chen Guosheng Liu 
We are grateful for financial support from 973 Program(No.2011CB808700);NSFC(Nos.21225210,20923005 and 21121062);STCSM(No.11JC1415000);the CAS/SAFEA International Partnership Program for Creative Research Teams.
A novel Ag-mediated dialkylation reaction of alkenes was disclosed,in which AgF was essential to activate C-H bond of acetonitrile.This reaction provided an efficient way to nitrile-containing spirooxindoles from read...
关键词：SPIROOXINDOLES activated alkenes silver fluoride ACETONITRILE C-H bond cleavage 
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