ISATIN

作品数:49被引量:63H指数:5
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相关领域:理学医药卫生更多>>
相关作者:侯琳杨欣田之悦薛英迟晓伟更多>>
相关机构:青岛大学扬州大学浙江海洋大学四川大学更多>>
相关期刊:《Journal of Chemistry and Chemical Engineering》《Open Journal of Inorganic Chemistry》《Chinese Journal of Structural Chemistry》《Journal of Energy Chemistry》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划青岛市科技局基金北京市自然科学基金更多>>
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Visible Light-Induced Umpolung Synthesis of 3,3-Disubstituted Oxindoles via the Substrate-Photosensitive Strategy
《Chinese Journal of Chemistry》2025年第4期431-436,共6页Jingjing Yang Tingting Wang Benhui Sui Hongyu Wang Bo Tang 
support from the National Natural Science Foundation of China(22377113,21927811,22134004);the Taishan Scholar Program of Shandong Province(tsqn202306103);the Fundamental Research Funds for the Central Universities(Ocean University of China)is greatly appreciated.
3,3-Disubstituted oxindoles,forming the core of extensive bioactive natural products and drugs,attract tremendous efforts to develop efficient methods for their preparation.Here,a photocatalyst-free approach for the s...
关键词:Umpolung synthesis Photocatalysis α-Amino radical Isatin-derived imines 3-Substituted 3-aminooxindoles 
Fluorinated poly(p-triphenylene isatin)anion exchange membranes based on hydrophilic hydroxyl side chain modulation for fuel cells
《Journal of Energy Chemistry》2025年第1期702-709,共8页Yiman Gu Yanchao Zhang Zhanyu Li Yijia Lei Baozeng Sun Xiaoyu Yu Zhe Wang 
Natural Science Foundation of China(grant nos 22075031);Jilin Provincial Science&Technology Department(grant nos 20220201105GX);Jilin Provincial Development and Reform Commission(grant nos 2023C034-4)。
The development of alkaline fuel cells is moving forward at an accelerated pace,and the application of ether-free bonded polymers to anion exchange membranes(AEMs)has been widely investigated.However,the question of ...
关键词:Anion exchange membranes Poly(p-terphenylene isatin) Hydrophilic-hydrophobic phase separation Fluorinated group 
Synergistic functionalization of poly(p-terphenyl isatin) anion exchange membrane with quaternary ammonium and piperidine cations for fuel cells
《Industrial Chemistry & Materials》2024年第1期141-153,共13页Yiman Gu Yanchao Zhang Zhe Wang Di Liu Yan Wang Tianming Dong Song Wang Zhanyu Li Jingyi Wu Yijia Lei 
The authors gratefully acknowledge the financial support of this work by Natural Science Foundation of China(grant no 22075031);Jilin Provincial Science&Technology Department(grant no 20220201105GX)。
Research on anion exchange membrane fuel cells(AEMFCs)mainly focuses on the membrane module,and improving its performance has always been the focus of researchers.To create high-performance anion exchange membranes(AE...
关键词:Multi-cation Ether-free polymer Alkaline resistance Microphase separation 
Construction of chiral 3-alkenyl-3-substituted oxindoles by stereoselective direct alkenylation of isatin derivatives and 3-vinylindoles
《Chinese Chemical Letters》2022年第12期5106-5110,共5页Xiang Sun Kuiliang Li Shuangshuang Zhao Zhenggen Zha Zhiyong Wang 
support from the National Natural Science Foundation of China(No.21772185);supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB20000000).
An efficient asymmetric alkenylation between 3-vinylindoles and isatin derivatives was developed under catalysis of a chiral copper complex.A series of optically active 3-alkenyl-3-substituted oxindoles were obtained ...
关键词:Asymmetric reaction Direct alkenylation Chiral Cu(Ⅱ)-complex 3-Vinylindole Isatin derivatives 
Construction of Chiral All-Carbon Quaternary Stereocenters by Asymmetric Friedel-Crafts Reaction of Isatin Derivatives被引量:1
《Chinese Journal of Chemistry》2022年第2期195-200,共6页Jindong Li Wenjing Lu Yangmian Lu Zhenggen Zha Zhiyong Wang 
Un der the catalysis of chiral Cu(ll)complex,C2 and C3 alkylati on of pyrrole and C3 alkylation of in dole were realized simulta neously.The chiral oxindole skeleton with an all-carb on quater nary stereogenic cen ter...
关键词:Asymmetric synthesis CHEMOSELECTIVITY Enan tioselectivity Nucleophilic addition OXINDOLE 
Bis-isatin derivatives: design, synthesis, and biological activity evaluation as potent dimeric DJ-1 inhibitors被引量:3
《Acta Pharmacologica Sinica》2021年第7期1160-1170,共11页Xiao-bing Chen Hai-ying Zhu Kun Bao Li Jiang Hong Zhu Mei-dan Ying Qiao-jun He Bo Yang Rong Sheng Ji Cao 
This work was supported by grants from the National Natural Science Foundation of China(No.81773757 to MDY,No.81402951 to JC);the National Science Technology Major Project"Key New Drug Creation and Manufacturing Program/China(2018ZX09711002-003-008 to HZ);and the Zhejiang Provincial Natural Science Foundation(No.Y18H310005 to JC).
The PARK7 gene (encode DJ-1 protein) was first discovered as an oncogene and later found to be a causative gene for autosomal recessive early onset Parkinson’s disease. DJ-1 has been proposed as a potential therapeut...
关键词:DJ-1 inhibitor DM10 isatin derivatives HOMODIMER anticancer therapy apoptosis ferroptosis STK793590 
Lewis base catalyzed ring-expansion of isatin with 2,2,2-trifluorodiazoethane(CF3CHN2):An efficient route to3-hydroxy-4-(trifluoromethyl)quinolinones
《Chinese Chemical Letters》2020年第6期1568-1571,共4页Shuaipeng Lv Yunfang Sun Yue Xu Shihai Yang Lei Wang 
financial support from the National Natural Science Foundation of China(No.81602977);the CAMS Innovation Fund for Medical Sciences(Nos.2019-RC-HL-010,2017-I2M-1013);the Science and Technology Development Project of Jilin Province of China(No.20190304050YY);China Association of Chinese Medicine(No.2017QNRC001)。
A Lewis base catalyzed ring expansion of isatin with 2,2,2-trifluorodiazoethane(CF3 CHN2)is developed.It is characterized that the merge of tetramethylethylenediamine and CF3 CHN2 generates reactive triazene intermedi...
关键词:RING-EXPANSION Lewis base HETEROCYCLE QUINOLINONES TRIAZENE 
Atroposelective Synthesis of 3,3'-Bisindoles Bearing Axial and Central Chirality:Using Isatin-Derived Imines as Electrophiles被引量:7
《Chinese Journal of Chemistry》2020年第6期583-589,共7页Feng-Tao Sheng Zhi-Min Li Yi-Zhu Zhang Li-Xing Sun Yu-Chen Zhang Wei Tan Feng Shi 
financial support from NSFC(Nos.21772069 and 21831007);Six Kinds of Talents Project of Jiangsu Province(SWYY-025).
An atroposelective synthesis of a new class of 3,3'-bisindoles bearing axial and central chirality has been established via catalytic asymmetric addition reactions using isatin-derived imines as electrophiles(23 examp...
关键词:INDOLE chiral AXIAL 
Synthesis, Characteristic and Antimicrobial Activity of Some New Spiro[indol-thiazolidon-2,4-diones] and Bis(5-fluorospiro[indoline-3,2’-thiazolidine]-2,4’-dione) Probes
《International Journal of Organic Chemistry》2020年第2期77-87,共11页Abeer N. Al-Romaizan 
In a search for new antimicrobial agents, some new spiro[indol-thiazolidon- 2,4-diones] (6a-c) were synthesized by condensation of 5-substituted isatins 1 with sulfanilamide in MeOH, ...
关键词:SYNTHESIS Spiroindoline-Thiazolidine Mercaptoacetic Acid Antimicrobial 5-Substituted Isatin SULFANILAMIDE 
Benzofuran-isatin-hydroxylimine/thiosemicarbazide hybrids:Design,synthesis and in vitro anti-mycobacterial activity evaluation被引量:2
《Chinese Chemical Letters》2019年第3期653-655,共3页Yaohuan Zhang Ruo Wang Tesen Zhang Weitao Yan Yihong Chen Yanping Zhang Muyang Zhou 
A series of novel benzofuran-isatin-hydroxylimine/thiosemicarbazide hybrids were designed, synthesized and evaluated for their in vitro anti-TB activities against drug-sensitive MTB H_(37)Rv and MDR-TB isolates as wel...
关键词:BENZOFURAN ISATIN Hybrid compounds Anti-mycobacterial Anti-tubercular Multi-drug resistant STRUCTURE-ACTIVITY relationship 
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