supported by the National Natural Science Foundation of China (22271065,22271314);the Guangzhou Basic and Applied Research (202201010396)。
Herein,we disclose a novel copper-catalyzed C(sp)-H aryl amination of terminal alkynes with anthranils,enabling the rapid generation of highly reactive secondary N-aryl ynamines for the modular synthesis of structural...
financial support from the National Natural Science Foundation of China(No.81602977);the CAMS Innovation Fund for Medical Sciences(Nos.2019-RC-HL-010,2017-I2M-1013);the Science and Technology Development Project of Jilin Province of China(No.20190304050YY);China Association of Chinese Medicine(No.2017QNRC001)。
A Lewis base catalyzed ring expansion of isatin with 2,2,2-trifluorodiazoethane(CF3 CHN2)is developed.It is characterized that the merge of tetramethylethylenediamine and CF3 CHN2 generates reactive triazene intermedi...
financial support from the National Natural Science Foundation of China(No.81602972);Guangdong Natural Science Funds for Distinguished Young Scholar(No.2018B030306017);Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme(2018)。
An efficient asymmetric and enantio-swithchable organocatalytic[3+3]annulation reaction using MBH-2-naphthoates of nitroalkenes and 4-hydroxyquinolin-2(1H)-ones has been developed.Densely substituted tetrahydropyrano[...
the Chongqing Research Program of Basic Research and Frontier Technology(Nos.cstc2015jcyj A1328 and cstc2015zdcy-ztzx0191);the Scientific Research Foundation of Chongqing University of Arts and Sciences(Nos.R2013XY01 and R2013XY02);Sichuan Provincial Science Fund for Distinguished Young Scholars(No.2015JQO055)
A series of quinolino[3,4-b]quinoxalin-6(5H)-ones have been synthesized using an Ugi/deprotection/cyclization(UDC) strategy, followed by a nucleophilic aromatic substitution reaction. This facile microwave-assiste...