the National Key R&D Program of China(grant no.2021YFF0701600);the National Natural Science Foundation of China(grant no.22225103);Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs,Shanghai Jiao Tong University,and the China Postdoctoral Science Foundation(grant nos.2020M680021 and 2021T140366),which was greatly appreciated.
Selective reduction of readily available N-heteroarenes is important in both organic synthesis and chemical biology.Herein,we describe ligand-controlled regiodivergent hydroboration of quinolines using well-defined am...
the National Natural Science Foundation of China(Nos.22371007,22071005);the Peking University Medicine Fund for world's leading discipline or discipline clusterdevelopment(BMU2022DJXK002).
A mild and practical method for synthesizing fluorinated quinoline derivatives,which have a wide range of applications in pharmaceuticals,materials,and organic synthesis,was described through C—F bond insertion into ...
supported by the National Natural Science Foundation of China (22271065,22271314);the Guangzhou Basic and Applied Research (202201010396)。
Herein,we disclose a novel copper-catalyzed C(sp)-H aryl amination of terminal alkynes with anthranils,enabling the rapid generation of highly reactive secondary N-aryl ynamines for the modular synthesis of structural...
the National Natural Science Foundation of China (Nos. 22101074, 21877206, and 21772032);the 111 Project (No. D17007);Excellent Youth Foundation of Henan Scientific Committee (No. 222300420012);China Postdoctoral Science Foundation (No. 2019M660173);the Natural Science Foundation of Henan Province (No. 202300410233)。
Atom-and step-economy in IBX assisted diversity-oriented synthesis is achieved with a versatile AQ auxiliary α-amino acid analogs offering rapid access to polycyclic spiro-quinolines featuring a quaternary stereocent...
Foundation of the National Natural Science Foundation of China(No.22101212);“Climbing Program”(No.pdjh2021a0505)Special Funds;Science Foundation for Young Teachers of Wuyi University(No.2019td06);Guangdong Basic and Applied Basic Research Foundation(Nos.2019A1515110866,2019A1515110522);College Students Innovation and Entrepreneurship Training Program of Wuyi University(Nos.202111349020,202111349308S)for financial support。
In this study,a method was developed to form C(sp^(3))-C(sp^(2))bonds via copper catalyst-promoted cross coupling of 2-methylquinoline and in-situ-activated 3-haloisoquinoline under mild conditions.The multi-component...
Financial support from the National Natural Science Foundation of China(Nos.21871226 and 21572194);the Hunan Provincial Natural Science Foundation of China(No.2020JJ5531);the Open Fund of Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates,Guangzhou 510640,China(South China University of Technology)(No.2019B030301003);the Undergraduate Investigated Study and Innovated Experiment Plan from Ministry of Education of China and Hunan Province is gratefully acknowledged.
An iron-catalyzed strategy for the rapid synthesis of indolo[2,3-c]quinolines has been developed.This cascade reaction involving alcohol oxidation,nitro reduction,and oxidative annulation was achieved in a one-pot.The...
Developing chiral solid catalysts for asymmetric catalysis is desirable for the elimination of homogeneous catalysis flaws but remains an immense challenge.Herein,we report the immobilization of TsDPEN on SBA‐15 with...
the National Natural Science Foundation of China(No.21772202,21831008);Beijing Municipal Science&Technology Commission(No.Z191100007219009);Beijing National Laboratory for Molecular Sciences(No.BNLMS-CXXM201901)。
Manganese-catalyzed hydrogenation of unsaturated molecules has made tremendous progresses recently benefiting from non-innocent pincer or bidentate ligands for manganese.Herein,we describe the hydrogenation of quinoli...
the National Natural Science Foundation of China(Nos.21602119,21702013);the Foundation of He’nan Educational Committee(No.16A150057);Program for Science and Technology Innovation Talents in Universities of Henan Province(No.19HASTIT033);the Beijing Natural Science Foundation(No.2184115);the Fundamental Research Funds for the Central Universities(Nos.XK1802-6,buctrc201721)。
Reported herein is the first example of electrochemical selenocyanation of imidazo[1,5-a]quinolines with KSeCN under metal catalyst-and chemical oxidant-free conditions.This sustainable strategy shows a broad scope an...
financial support from the National Natural Science Foundation of China(No.81602972);Guangdong Natural Science Funds for Distinguished Young Scholar(No.2018B030306017);Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme(2018)。
An efficient asymmetric and enantio-swithchable organocatalytic[3+3]annulation reaction using MBH-2-naphthoates of nitroalkenes and 4-hydroxyquinolin-2(1H)-ones has been developed.Densely substituted tetrahydropyrano[...