云南高校图书馆联盟文献共享服务平台- QUINOLONE

QUINOLONE: 作品数：38被引量：44H指数：4; 导出分析报告; 相关领域：医药卫生理学更多>>; 相关作者：周成合范家伟茆海丰王春梅难波恒雄更多>>; 相关机构：西南大学中国医药大学富山医科药科大学连云港市第一人民医院更多>>; 相关期刊：《Chinese Herbal Medicines》《Open Journal of Medical Microbiology》《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》更多>>; 相关基金：国家自然科学基金国家教育部博士点基金重庆市自然科学基金国家重点基础研究发展计划更多>>

NO inhibitory constituents from Glycosmis craibii var.glabra: 《Chinese Journal of Natural Medicines》2024年第11期1040-1046,共7页CHEN Hongwei DING Meng LIN Jun YUAN Shuo ZENG Kewu TU Pengfei JIANG Yong; supported by National Natural Science Foundation of China(Nos.81973199,82173949,and 81773864);the Key Research and Development Project of Shandong Province(No.2021CXGC010507)。; Six novel compounds,comprising three quinolones(1a,1b,and 2)and three flavanones(3-5),along with seven known analogs(6-13),were isolated from the 95%EtOH extract of the stems and leaves of Glycosmis craibii var.glabra...; 关键词：Glycosmis craibii var.glabra QUINOLONE FLAVANONE NO inhibition

C—F Bond Insertion into Indoles with CHBr_(2)F:An Efficient Method to Synthesize Fluorinated Quinolines and Quinolones: 《Chinese Journal of Chemistry》2024年第10期1128-1132,共5页Chao Li Lei Chen Hongye Wang Zixi Yan Bin Lyu Weiping Lyu Changwei Jiang Dehua Lu Jiaxing Li Ning Jiao Song Song; the National Natural Science Foundation of China(Nos.22371007,22071005);the Peking University Medicine Fund for world's leading discipline or discipline clusterdevelopment(BMU2022DJXK002).; A mild and practical method for synthesizing fluorinated quinoline derivatives,which have a wide range of applications in pharmaceuticals,materials,and organic synthesis,was described through C—F bond insertion into ...; 关键词：Skeleton edit Fluorocarbene Ring expansion QUINOLINE QUINOLONE

Design,synthesis,and evaluation of fluoroquinolone derivatives as microRNA-21 small-molecule inhibitors: 《Journal of Pharmaceutical Analysis》2022年第4期653-663,共11页Yuan-Yuan Hei Si Wang Xiao-Xiao Xi Hai-Peng Wang Yuanxu Guo Minhang Xin Congshan Jiang Shemin Lu San-Qi Zhang; Financial support from the National Natural Science Foundation of China(Grant No.:81673354)is gratefully acknowledged.; MicroRNA-21(miRNA-21)is highly expressed in various tumors.Small-molecule inhibition of miRNA-21 is considered to be an attractive novel cancer therapeutic strategy.In this study,fluoroquinolone derivatives A1eA43 wer...; 关键词：Quinolone derivatives Small-molecule miRNA-21 inhibitor Antitumor agent Drug design

Efficacy of Cefoperazone Sodium and Sulbactam Sodium Combined with Quinolone in the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease: 《外文科技期刊数据库(文摘版)医药卫生》2021年第12期016-018,共5页XIE Wenmin; Objective: to explore the treatment effect of different ways in patients with acute exacerbation of COPD. Methods: according to the inclusion criteria and exclusion criteria, 70 patients with acute exacerbation of COP...; 关键词：acute exacerbation of COPD QUINOLONE cefoperazone sodium sulbactam sodium PAO2 adverse reactions

Spectroscopic Investigations for the Six New Synthesized Complexes of Fluoroquinolones and Quinolones Drugs With Nickel(Ⅱ) Metal Ion:Infrared and Electronic Spectroscopy: 《光谱学与光谱分析》2021年第6期1976-1981,共6页Samar O.Aljazzar; the deanship of scientific Research at Princess Nourah bint Abdulrahman University through the Fast-track Research Funding program。; Quinolone has a broad spectrum of synthetic antibiotics with a strong therapeutic effect and quinolone is a term used for chemical treatments used to treat a powerful bacteria.Quinolones are divided into 4 generations...; 关键词：QUINOLONE FLUOROQUINOLONE NICKEL FTIR CHELATES UV-Vis Octahedral geometry

Evaluation of inpatients Clostridium difficile prevalence and risk factors in Cameroon被引量：1: 《Infectious Diseases of Poverty》2020年第4期172-172,共1页Ingrid Cécile Djuikoue Ernest Tambo Gildas Tazemda Omer Njajou Denise Makoudjou Vanessa Sokeng Morelle Wandji Charlène Tomi Aubain Nanfack Audrey Dayomo Suzie Lacmago Falubert Tassadjo Raissa Talla Sipowo Caroline Kakam Aicha Bibiane Djoko Clement Nguedia Assob Antoine Andremont Frédéric Barbut; Background Clostridium difficile,rarely found in hospitals,is a bacterium responsible for post-antibiotic diarrhea and Pseudomembranous Colitis(CPM).C.difficile selective pressure represents potential public health pr...; 关键词：Clostridium difficile PREVALENCE DIARRHEA Risk factors QUINOLONE CEPHALOSPORIN Cameroon

Genotypic Diversity and Characterization of Quinolone Resistant Determinants from Enterobacteriaceae in Yaoundé, Cameroon: 《Open Journal of Medical Microbiology》2020年第2期33-45,共13页Emilia Enjema Lyonga Mbamyah Michel Toukam Marie-Claire Okomo Assoumou Anthony M. Smith Celine Nkenfou Hortense Kamga Gonsu Anicette Chafa Betbeui Martha Tongo Mesembe Agnes Bedie Eyoh George Mondinde Ikomey Sinata Koulla-Shiro; Background: Enterobacteriaceae causes many types of infections which are often treated with quinolones and fluoroquinolone (Q/FQ). The resistance mechanisms to Q/FQ are usually associated with mutatio...; 关键词：ENTEROBACTERIACEAE Quinolone Resistance Plasmid-Mediated Quinolone Resistance qnr Genes

Update on quinolone-containing rescue therapies for Helicobacter pylori infection被引量：4: 《World Journal of Gastroenterology》2020年第15期1733-1744,共12页Hideki Mori Hidekazu Suzuki; Third generation of quinolones,such as levofloxacin and moxifloxacin,-containing regimens are often used in second-line or rescue treatment of Helicobacter pylori infection.However,the increasing antibiotic resistance...; 关键词：HELICOBACTER pylori LEVOFLOXACIN SITAFLOXACIN MOXIFLOXACIN GYRA Vonoprazan

Antioxidant, Cytotoxic, Thrombolytic and Antimicrobial Activity of <i>Zanthoxylum rhetsa</i>Root Bark with Two Isolated Quinolone Alkaloids: 《Pharmacology & Pharmacy》2019年第3期137-145,共9页Fatema Tuz Zohora Sheikh Nazrul Islam Shibbir Ahmed Khan Choudhury Mahmood Hasan Monira Ahsan; The background of this study was to investigate the antioxidant, cytotoxic, thrombolytic and antimicrobial activity of the petroleum ether (PE), carbon tetrachloride (CTC), chloroform (CF) and aqueous (AQ) soluble fra...; 关键词：ZANTHOXYLUM rhetsa ANTIOXIDANT THROMBOLYTIC Antimicrobial 8-Methoxy-n-Methylflindersine Zanthodioline

Molecular Modeling of Quinoline-Based Compounds as Potential Dual Inhibitors of Reverse Transcriptase and Integrase of HIV被引量：1: 《Computational Molecular Bioscience》2018年第3期122-148,共27页Alberto Cabrera Leonor Huerta Hernández Daniel Chávez José L. Medina-Franco; As follow-up of our past publication?[1], we propose that quinolones (as part of the pyridinone family) are capable to increase the number of interactions with HIV reverse transcriptase (RT) or integrase (IN) by addin...; 关键词：REVERSE Transcriptase INTEGRASE QUINOLONE Dual Inhibitor DOCKING

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