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Optimization of the Crystallization Process for Ceftriaxone Sodium, a Third-Generation Cephalosporin, Utilizing Response Surface Methodology: 《Medicinal Plant》2025年第2期14-18,共5页Yanxi LAI Furong ZHANG Jingyue ZHU Hao LIU Yizhang WANG Jing LI Shengjiu GU; Supported by Central Guided Local Science and Technology Development Funds(ZY20230102);Guilin Scientific Research and Technology Development Programme Project(2023010301-1,20220104-4);Guangxi Science and Technology Programme Project(GK AB24010263);Guangxi Innovation Driving Development Special Funds Project(GK AA22096020).; [Objectives] To optimize the crystallization process of ceftriaxone sodium using response surface methodology (RSM) for enhancing both the crystallization rate and the quality of the final product. [Methods] Four key ...; 关键词：Ceftriaxone sodium Response surface methodology(RSM) Crystallization process Process optimization

Extended spectrum cephalosporin(ESC)resistant Escherichia coli:trends and seasonality in the Netherlands from 2014 to 2022: 《Science in One Health》2024年第1期215-220,共6页Michael S.M.Brouwer Eduardo de Freitas Costa Anita Dame-Korevaar Adam P.Roberts Kees T.Veldman; m the Ministry of Agriculture,Nature and Food Quality in the Netherlands(grant number WOT-01-002-03.02);the Medical Research Council(MRC),Biotechnology and Biological Sciences Research Council(BBSRC),and Natural Environmental Research Council(NERC),which are all councils of UK Research and Innovation(grant number MR/W030578/1);from ZonMw(grant number 10570132110004)under the umbrella of the JPIAMR(Joint Programming Initiative on Antimicrobial Resistance)project STRESST.; Background:Antimicrobial resistance(AMR)in livestock and the environment likely contribute to the prevalence of AMR in humans with potential detrimental effects on human health.As such,annual mandatory monitoring of A...; 关键词：AMR Livestock Season ESBL Extended-spectrum cephalosporin-resistant

Advancing Cefuroxime Axetil through Nanotechnology: Enhancing Its Effectiveness: 《Journal of Bio-X Research》2024年第4期173-181,共9页Amit Yadav Nita Yadav Reetika Rawat Shipra Sharma Tapasvi Gupta Durga Prasad; Cefuroxime axetil,a second-generation cephalosporin antibiotic,has long been utilized to treat various bacterial infections.However,recent advances in nanotechnology have provided new directions for enhancing its effe...; 关键词：pharmacokinetic PHARMACODYNAMIC cephalosporin antibiotichas NANOTECHNOLOGY nanoformulations cefuroxime axetil enhancing its effectiveness

Analysis of Polymer Impurities in Cephalosporin Antibiotics: 《Medicinal Plant》2024年第5期22-26,30,共6页Shiqiang OU Yanxi LAI Peng XIE Hao LIU Shicheng LIU Jin QIN Yiping QIN Yizhang WANG Shengjiu GU; Supported by2023 Central Funds for Guiding Local Science and Technology Development(ZY20230102);Guilin City Scientific Research and Technology Development Plan Project(20220104-4).; [Objectives]To establish a HPLC-MS method for the determination of polymer impurities in cefathiamidine and its preparations.[Methods]Kromasil 100-5 C_(18) column(4.6 mm ×250 mm,5μm)was used for analysis;mobile phas...; 关键词：CEFATHIAMIDINE Cephalosporin polymer impurities Impurity analysis High Performance Liquid Chromatography-Mass Spectrometry

Molecular Characteristics of Cephalosporin-Resistant Neisseria gonorrhoeae Strains in China:A Retrospective Study: 《International Journal of Dermatology and Venereology》2024年第2期78-83,共6页Jin Zhang Xiao-Yu Zhu Jing-Wei Liu Yue-Ping Yin Shao-Chun Chen; supported by National Science and Technology Major Project(No.2018ZX10101001-004-003);Jiangsu Provincial high level health personnel"six one project"top talent project(No.LGY2019091); Objective:An increasing level of antimicrobial resistance to extended-spectrum cephalosporins has been reported,so we conducted this study to investigate the molecular characteristics of cephalosporin resistant Neisse...; 关键词：GONORRHEA resistance CEPHALOSPORIN CEFIXIME CEFTRIAXONE

Evaluation of inpatients Clostridium difficile prevalence and risk factors in Cameroon被引量：1: 《Infectious Diseases of Poverty》2020年第4期172-172,共1页Ingrid Cécile Djuikoue Ernest Tambo Gildas Tazemda Omer Njajou Denise Makoudjou Vanessa Sokeng Morelle Wandji Charlène Tomi Aubain Nanfack Audrey Dayomo Suzie Lacmago Falubert Tassadjo Raissa Talla Sipowo Caroline Kakam Aicha Bibiane Djoko Clement Nguedia Assob Antoine Andremont Frédéric Barbut; Background Clostridium difficile,rarely found in hospitals,is a bacterium responsible for post-antibiotic diarrhea and Pseudomembranous Colitis(CPM).C.difficile selective pressure represents potential public health pr...; 关键词：Clostridium difficile PREVALENCE DIARRHEA Risk factors QUINOLONE CEPHALOSPORIN Cameroon

Post-appendectomy pelvic abscess with extended-spectrum beta-lactamase producing Escherichia coli : A case report and review of literature被引量：1: 《World Journal of Clinical Cases》2018年第16期1175-1181,共7页Andrew Tse Rajkumar Cheluvappa Selwyn Selvendran; BACKGROUND Appendicitis, the inflammation of the appendix, is the most common abdominal surgical emergency requiring expedient surgical intervention. Extendedspectrum beta-lactamases(ESBLs) are bacterial enzymes that ...; 关键词：APPENDECTOMY APPENDICEAL ABSCESS Appendicitis BETA-LACTAM Antibiotic resistance BETA-LACTAMASE Carbanepem CEPHALOSPORIN Escherichia coli Extended-spectrum BETA-LACTAMASE Infection Pelvic ABSCESS Penicillin Case report

Clinical Pharmacokinetic and Bioequivalence Studies of Two Brands of Cephradine in Healthy Korean Using HPLC Method: 《Pharmacology & Pharmacy》2018年第7期279-292,共14页Hyun-Jin Kim Shin-Hee Kim Semi Kim Jae-Sung Ahn Ju-Seop Kang; The goal of our research was to compare the pharmacokinetics and evaluate the bioequivalence of two brands of cephradine 500 mg capsules in 24 normal Korean volunteers. The plasma samples were acquired at 13 time poin...; 关键词：BIOEQUIVALENCE CEPHALOSPORIN Antibiotic CEPHRADINE KOREAN VOLUNTEERS Pharmacokinetics

A GATA-type transcription factor AcAREB for nitrogen metabolism is involved in regulation of cephalosporin biosynthesis in Acremonium chrysogenum被引量：8: 《Science China(Life Sciences)》2017年第9期958-967,共10页Feifei Guan Yuanyuan Pan Jinyang Li Gang Liu; supported by the National Natural Science Foundation of China(31670091 and 31470177); In filamentous fungi,nitrogen metabolism is repressed by GATA-type zinc finger transcription factors.Nitrogen metabolite repression has been found to affect antibiotic production,but the mechanism is still poorly unde...; 关键词：AcareB Acremonium chrysogenum cephalosporin biosynthesis GATA-type transcription factor REGULATION

Selective Association between Cephalosporin, Quinolone, Macrolide, and Penicillin Antibiotic Consumption and Childhood Obesity in Europe被引量：1: 《Health》2015年第10期1306-1314,共9页Gabor Ternak Zs Edel Zs Feiszt J. Szekeres B. Visegrady I. Wittmann; The accelerated weight gain in productive animals as a result of feeding antibiotic enriched fodder has been well known for decades. The better energy harvest is the result of modified gut microbiota as a consequence ...; 关键词：Antibiotic Consumption CEPHALOSPORIN QUINOLONE MACROLIDE PENICILLIN CHILDHOOD OBESITY Adult OBESITY

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