PHARMACODYNAMIC

作品数：54被引量：117H指数：7
导出分析报告
相关领域：医药卫生更多>>
相关作者：牟珍珍姚庆宇王丽杰袁茵李静云更多>>
相关机构：北京大学更多>>
相关期刊：《Chinese Herbal Medicines》《Medicinal Plant》《Chinese Journal of Integrative Medicine》《Chinese Journal of Natural Medicines》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划北京市自然科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
A new strategy for pharmacodynamic substance screening and research on gut microbiota pathway mechanisms based on UPLC-Q-orbitrap-MS and 16S rRNA
《Journal of Traditional Chinese Medical Sciences》2025年第1期56-70,共15页Zhiying Yu Tong Li Jie Yang Jianghua He Weijiang Zhang Siyuan Li Yunpeng Qi Yihui Yin Ling Dong Wenjuan Xu 
supported by Fundamental Research Funds for the Central Universities(2022-ZXFZJJ-028).
Objective:To establish a progressive research strategy for“colonic components analysis-efficacy verification and mechanism exploration-gut microbiota”,screen pharmacodynamic substances,and investigate their mechanis...
关键词：COLON Gegen Qinlian decoction Gut microbiota Mechanism research Pharmacodynamic component screening TCM-gut microbiota interaction Ulcerative colitis 
Metformin—Pharmacokinetic and Pharmacodynamics Journey Through the Body
《Pharmacology & Pharmacy》2024年第12期466-477,共12页Alycia Lewis Kelley Williams Terry Oroszi 
Metformin is a commonly prescribed drug used to treat type 2 diabetes. The drug works by decreasing the amount of glucose the liver produces, increasing the sensitivity of muscle cells to insulin, and delaying the abs...
关键词：DIABETES METFORMIN PHARMACOKINETIC PHARMACODYNAMIC Personalized Medicine 
Advancing Cefuroxime Axetil through Nanotechnology: Enhancing Its Effectiveness
《Journal of Bio-X Research》2024年第4期173-181,共9页Amit Yadav Nita Yadav Reetika Rawat Shipra Sharma Tapasvi Gupta Durga Prasad 
Cefuroxime axetil,a second-generation cephalosporin antibiotic,has long been utilized to treat various bacterial infections.However,recent advances in nanotechnology have provided new directions for enhancing its effe...
关键词：pharmacokinetic PHARMACODYNAMIC cephalosporin antibiotichas NANOTECHNOLOGY nanoformulations cefuroxime axetil enhancing its effectiveness 
Reveal the pharmacodynamic substances and mechanism of an edible medicinal plant Rhodiola crenulate in DSS-induced colitis through plasma pharmacochemistry and metabolomics
《Food Science and Human Wellness》2024年第4期2116-2131,共16页Yu Peng Xiaoao Xiao Tingting Ji Xinyuan Wang Yixuan Xu Jianbo Xiao Hui Cao Zhiyong Chen Huifan Liu Yuanqing Gao Hongxun Tao 
supported by China Postdoctoral Science Foundation(2021M701759);Nanjing Medical University Science and Technology Development Fund(NMUB20210012);Jiangsu Provincial Outstanding Postdoctoral Programme(2022ZB430);National Natural Science Foundation of China(grant No.81873654,82201579);Open Research Fund of State Key Laboratory of Southwestern Chinese Medicine Resources(SKLTCM2022020);Guangdong Provincial Key Laboratory of Lingnan Specialty Food Science and Technology(kjzr220009);Zhejiang Province Key Laboratory of Medical Electronics and Digital Health(MEDH2022016)。
Rhodiola crenulate is the edible medicinal herbal medicine widely used for altitude sickness in China.Interestingly,our previous work has found that R.crenulate extract(RCE)could significantly improve the pathology as...
关键词：Rhodiola crenulate COLITIS Chemical characterization Plasma pharmacochemistry Metabolomics 
Pharmacodynamic Experiment of Dachengqi Decoction and Separated Decoction on Incomplete Intestinal Obstruction in Rats
《Medicinal Plant》2024年第4期107-110,共4页Jiangcun WEI Xiumei MA Bing QING Meiyan QIU Qingmei DENG Hong LEI Zengyan YANG Zujie QIN 
2023 Young and Middle-aged University Teachers Basic Scientific Research Ability Improvement Project in Guangxi(2023KY0299);High-level Key Discipline Construction Project of Traditional Chinese Medicine of National Administration of Traditional Chinese Medicine(zyyzdxk-2023165);Talent Training Project of Guangxi International Zhuang Medicine Hospital—"Young Seedling Project"(2022001);Guangxi Traditional Chinese Medicine Multidisciplinary and Interdisciplinary Innovation Team Project(GZKJ2309);High-level Talent Cultivation Innovation Team Funding Project of Guangxi University of Chinese Medicine(2022A008);2023 Three-Year Action Plan Project for High-Level Talent Team Construction of Guangxi International Zhuang Medicine Hospital(GZCX20231203,GZCX20231202).
[Objectives]To investigate the effect and mechanism of Dachengqi Decoction and separated decoction on incomplete intestinal obstruction in rats.[Methods]80 healthy SD rats were selected to establish incomplete intesti...
关键词：Dachengqi Decoction Separated decoction Incomplete intestinal obstruction Inflammatory factor 
Differential metabolite analysis of the pharmacodynamic differences between different ratios of Dahuang(Radix Et Rhizoma Rhei Palmati)-Taoren(Semen Persicae) herb pair被引量：1
《Journal of Traditional Chinese Medicine》2024年第3期515-523,共9页WANG Xiang HUANG Jianping WANG Yupeng WANG Qilong JING Yajiang ZHANG Gang PENG Liang GAO Jing WANG Hongyan YAN Yonggang 
National Major Natural Science:Study on the Dose-effect Relationship and Compatibility Mechanism of Core Medicine in Taohe Chengqi Decoction Prescription on "Removing Stasis And Dissipating Heat" of Taoren Rhubarb (No. 81973592);Project of the Administration of Traditional Chinese Medicine of Shaanxi Province:Study on the Compatibility of the Classic Prescription Taohe Chengqi Decoction "Expelling Stasis And Expelling Heat" Based on Drug Interaction (2021-GJ-JC004);Supported by Discipline Innovation Team Project on Quality Evaluation and Resource Development of "Qin Medicine",Shaanxi University of Chinese Medicine (2019-QN01)。
OBJECTIVE: To explore the material basis of the difference of efficacy of Dahuang(Radix Et Rhizoma Rhei Palmati)-Taoren(Semen Persicae)(DT) drugs with different proportions. METHODS: Samples of different ratios of Dah...
关键词：metabolomics metabolic networks and pathways differential metabolites Dahuang(Radix Et Rhizoma Rhei Palmati) Taoren(Semen Persicae) kernel drug pairs 
Insulin therapy in type 2 diabetes: Insights into clinical efficacy, patient-reported outcomes, and adherence challenges
《World Journal of Diabetes》2024年第5期828-852,共25页Mahmoud Emad-Eldin Gehan F Balata Eman A Elshorbagy Mona S Hamed Mohamed S Attia 
Insulin therapy plays a crucial role in the management of type 2 diabetes as the disease progresses.Over the past century,insulin formulations have undergone significant modifications and bioengineering,resulting in a...
关键词：ADHERENCE DIABETES INSULIN Patient-reported outcomes PHARMACOKINETIC PHARMACODYNAMIC 
Advances in Research Methods of Pharmacodynamic Substances in Traditional Chinese Medicines and Their Application in the Teaching of Traditional Chinese Medicine Analysi
《Journal of Contemporary Educational Research》2024年第5期97-102,共6页Jiangwei Tian 
Jiangsu Province Higher Education Teaching Reform Research Key Project“Research and Reform of Industry-Needed Pharmacy Engineering Talents Incubation Mode from the Perspective of Industry-Teaching Integration and Innovation Drive”(2023JSJG077)。
With the continuous progress of science and technology,the research methods of pharmacodynamic substances in traditional Chinese medicine are developing,and the application of these methods in teaching is becoming mor...
关键词：Traditional Chinese medicine Pharmacodynamic substances Teaching of traditional Chinese medicine analysis Teaching application 
Pharmacodynamic advantages and characteristics of traditional Chinese medicine in prevention and treatment of ischemic stroke被引量：8
《Chinese Herbal Medicines》2023年第4期496-508,共13页Hanyu Zhang Bowen Jin Xinyu You Pengrong Yi Hong Guo Lin Niu Qingsheng Yin Jiangwei Shi Yanjun Zhang Pengwei Zhuang 
supported by the National Natural Science Foundation of China (No. 82174112);the Science and Technology Project of Haihe Laboratory of Modern Chinese Medicine (No. 22HHZYSS00015)。
Ischemic stroke(IS) is a severe cerebrovascular disease with a high incidence, mortality, and disability rate. The first-line treatment for IS is the use of recombinant tissue plasminogen activator(r-t PA).Regrettably...
关键词：ischemic stroke traditional Chinese medicine syndrome differentiation and treatment traditional Chinese medicine dominant disease secondary prevention 
Optimization of Compound Coptis Ointment Extraction through the Integration of Pharmacodynamic Indices and Orthogonal Test
《Medicinal Plant》2023年第5期32-35,共4页Jin ZHOU Xiuli ZHOU Yu ZHOU Ming MEI Qiang GAO Xinguo LIU 
Supported by Key Research Project of Wuhan Municipal Health Commission(WZ21A08).
[Objectives]To determine the optimal reflux extraction process conditions for Compound Coptis Ointment.[Methods]The study employed the orthogonal experimental design method and drug-sensitive disc agar diffusion metho...
关键词：Compound Coptis Ointment Orthogonal test Antibacterial test Extraction process 
全选清除导出
共6页<123456>
检索报告 对象比较 聚类工具 使用帮助 返回顶部