PENICILLIN

作品数:74被引量:115H指数:7
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相关领域:医药卫生更多>>
相关作者:王海雁高扬帆周叶红王丹丹双少敏更多>>
相关机构:山西大学河南科技学院上海瀚淇国际贸易有限公司山西医科大学更多>>
相关期刊:更多>>
相关基金:国家自然科学基金山西省自然科学基金国家科技攻关计划河南省自然科学基金更多>>
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Correction:Spontaneous mutations and mutational responses to penicillin treatment in the bacterial pathogen Streptococcus pneumoniae D39
《Marine Life Science & Technology》2024年第3期576-577,共2页Wanyue Jiang Tongtong Lin Jiao Pan Caitlyn E.Rivera Clayton Tincher Yaohai Wang Yu Zhang Xiang Gao Yan Wang Ho-Ching T.Tsui Malcolm E.Winkler Michael Lynch Hongan Long 
Due to technical errors,Ho-Ching T.Tsui and Malcolm E.Winkler,both collaborators who made substantial contributions to this work and were previously acknowledged,did not receive emails regarding authorship consent and...
关键词:WINKLER EMAIL CONTRIBUTIONS 
Spontaneous mutations and mutational responses to penicillin treatment in the bacterial pathogen Streptococcus pneumoniae D39
《Marine Life Science & Technology》2024年第2期198-211,共14页Wanyue Jiang Tongtong Lin Jiao Pan Caitlyn ERivera Clayton Tincher Yaohai Wang Yu Zhang Xiang Gao Yan Wang Ho‑Ching T.Tsui Malcolm E.Winkler Michael Lynch Hongan Long 
financially supported by Laoshan Laboratory(LSKJ202203203);the National Natural Science Founda-tion of China(31961123002,32270435);the Fundamental Research Funds for the Central Universities of China(202041001);the Shan-dong Provincial Natural Science Foundation(ZR2023QC191);the Postdoctoral Fellowship Program of CPSF under Grant Number GZC20232504;the Multidisciplinary University Research Initiative Award from the US Army Research Office(W911NF-09-1-0444);National Institutes of Health award(R35-GM122566 to ML)and(R35-GM131767 to MEW).
Bacteria with functional DNA repair systems are expected to have low mutation rates due to strong natural selection for genomic stability.However,our study of the wild-type Streptococcus pneumoniae D39,a pathogen resp...
关键词:Neutral evolution Mutation spectrum ANTIBIOTICS DNA mismatch repair Oxidative damage repair 
Zhang Weishe n:A Pion eer in the Developme nt and In dustrial Production of Penicillin in New China被引量:1
《Chinese Medical Sciences Journal》2022年第3期282-286,I0015,共6页Bin Yu Fumin Huang Guoxing Tang Jing Liu 
北京市社会科学基金重点项目“北京医学博物馆的历史文化与传播创新研究”(21LSA001)。
The research and development of penicillin started with dificulty before 1949 and achieved certain results.In 1951,after the founding of the People’ s Republic of China,Zhang Weishen,as the only Chinese scientist who...
关键词:PENICILLIN ANTIBIOTICS research and development industrial production Zhang Weishen 
Discussion on the dimerization reaction of penicillin antibiotics
《Journal of Pharmaceutical Analysis》2022年第3期481-488,共8页Qizhang Wu Xia Zhang Jiaxin Du Changqin Hu 
supported by the National Major Scientific and Technological Special Project for“Significant New Drugs Development”(Grant No.:2017ZX09101001-007).
Penicillins are one type of the most important antibiotics used in the clinic.Control of drug impurity profiles is an important part of ensuring drug safety.This is particularly important in penicillins where polymeri...
关键词:PENICILLINS Dimerization reaction Theoretical calculations LC/MS 
Comparative Study on the Efficacy of Chlorogenic Acid and Penicillin Solution in Flos Lonicerae on Mice Infected with Hemolytic Streptococcus
《外文科技期刊数据库(文摘版)自然科学》2022年第5期032-036,共5页HONGLingjie DUANWenyu 
Objective: to explore the therapeutic effect of chlorogenic acid and penicillin aqueous solution in Flos Lonicerae on mice infected by hemolytic streptococcus. Methods: 80 healthy adult mice were randomly divided into...
关键词:chlorogenic acid aqueous solution aqueous penicillin solution hemolytic streptococcus THERAPEUTIC 
Treatment of Helicobacter pylori infection in the presence of penicillin allergy被引量:1
《World Journal of Gastroenterology》2021年第44期7661-7668,共8页Amit Kumar Dutta Perminder Singh Phull 
Therapy of Helicobacter pylori(H.pylori)requires a combination of antibiotics together with an acid suppressing agent;most treatment regimens include Amoxicillin as one of the antibiotics,which is an important constit...
关键词:Helicobacter pylori Infection TREATMENT Penicillin-allergy STOMACH DUODENUM 
Theoretical Analysis of Structural Characteristics of Morin Rearrangement for Cephalosporins Prepared from Penicillin Sulfoxide被引量:1
《Chinese Journal of Structural Chemistry》2020年第9期1594-1600,1554,共8页CHEN Guo-Hua JIANG Ning XIANG Hai-Yan DU Hai-Bo 
supported by Key Laboratories of Fine Chemicals and Surfactants in Sichuan Provincial Universities (2016JXY01);the Opening Project of Key Laboratory of Green Chemistry of Sichuan Institutes of Higher Education (LYJ1105);Sichuan University of Science and Engineering talent introduction fund (2017RCL19)。
The structure of penicillin sulfoxide is rearranged to cephalosporins by the Morin rearrangement. It is a unit reaction for the preparation of various types of cephalosporins. In order to make better use of the reacti...
关键词:penicillin G sulfoxide morin rearrangement reaction mechanism theoretical study CEPHALOSPORINS 
Synthesis and Spectroscopic Investigations of Four New Y(Ⅲ), Ge(Ⅳ), W(Ⅵ) and Si(Ⅳ) Penicillin Antibiotic Drug Complexes
《光谱学与光谱分析》2019年第9期2982-2988,共7页Abeer A.El-Habeeb Moamen S.Refat 
A four new penicillinate complexes were prepared through the chemical interactio ns of penicillin potassium salt (Pin) with YCl 3, GeCl 4, WCl 6 and SiCl 4 m etal ions. These metal complexes were characterized using s...
关键词:PENICILLIN YTTRIUM GERMANIUM TUNGSTEN SI licon FTIR COMPLEXATION Biological 
Welcome Back to the Pre-Penicillin Era.Why We Desperately Need New Strategies in the Battle Against Bacterial Pathogens被引量:5
《Infectious Microbes & Diseases》2019年第2期33-33,共1页Sebastian Leptihn 
In 2023,one hundred years will have passed since penicillin was discovered.My parents'generation was bor around the time penicillin was introduced(in 1942),raising their children when the last class of antibiotics was...
关键词:consequences LIFETIME realization 
Analysis of the results of Treponema Pallidum DNA in serum and vaginal fluid of patients with latent syphilis before and after treatment
《China Medical Abstracts(Internal Medicine)》2018年第4期206-207,共2页GAO Hong 
Objective To investigate the infectivity of serum and vaginal fluid in early cases and late latent cases of syphilis.Methods From January 2015 to December 2015,sixty-eight female patients with latent syphilis were enr...
关键词:INVESTIGATE the infectivity benzathine PENICILLIN 
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