Due to technical errors,Ho-Ching T.Tsui and Malcolm E.Winkler,both collaborators who made substantial contributions to this work and were previously acknowledged,did not receive emails regarding authorship consent and...
financially supported by Laoshan Laboratory(LSKJ202203203);the National Natural Science Founda-tion of China(31961123002,32270435);the Fundamental Research Funds for the Central Universities of China(202041001);the Shan-dong Provincial Natural Science Foundation(ZR2023QC191);the Postdoctoral Fellowship Program of CPSF under Grant Number GZC20232504;the Multidisciplinary University Research Initiative Award from the US Army Research Office(W911NF-09-1-0444);National Institutes of Health award(R35-GM122566 to ML)and(R35-GM131767 to MEW).
Bacteria with functional DNA repair systems are expected to have low mutation rates due to strong natural selection for genomic stability.However,our study of the wild-type Streptococcus pneumoniae D39,a pathogen resp...
The research and development of penicillin started with dificulty before 1949 and achieved certain results.In 1951,after the founding of the People’ s Republic of China,Zhang Weishen,as the only Chinese scientist who...
supported by the National Major Scientific and Technological Special Project for“Significant New Drugs Development”(Grant No.:2017ZX09101001-007).
Penicillins are one type of the most important antibiotics used in the clinic.Control of drug impurity profiles is an important part of ensuring drug safety.This is particularly important in penicillins where polymeri...
Objective: to explore the therapeutic effect of chlorogenic acid and penicillin aqueous solution in Flos Lonicerae on mice infected by hemolytic streptococcus. Methods: 80 healthy adult mice were randomly divided into...
Therapy of Helicobacter pylori(H.pylori)requires a combination of antibiotics together with an acid suppressing agent;most treatment regimens include Amoxicillin as one of the antibiotics,which is an important constit...
supported by Key Laboratories of Fine Chemicals and Surfactants in Sichuan Provincial Universities (2016JXY01);the Opening Project of Key Laboratory of Green Chemistry of Sichuan Institutes of Higher Education (LYJ1105);Sichuan University of Science and Engineering talent introduction fund (2017RCL19)。
The structure of penicillin sulfoxide is rearranged to cephalosporins by the Morin rearrangement. It is a unit reaction for the preparation of various types of cephalosporins. In order to make better use of the reacti...
A four new penicillinate complexes were prepared through the chemical interactio ns of penicillin potassium salt (Pin) with YCl 3, GeCl 4, WCl 6 and SiCl 4 m etal ions. These metal complexes were characterized using s...
In 2023,one hundred years will have passed since penicillin was discovered.My parents'generation was bor around the time penicillin was introduced(in 1942),raising their children when the last class of antibiotics was...
Objective To investigate the infectivity of serum and vaginal fluid in early cases and late latent cases of syphilis.Methods From January 2015 to December 2015,sixty-eight female patients with latent syphilis were enr...