supported by the National Major Scientific and Technological Special Project for“Significant New Drugs Development”(Grant No.:2017ZX09101001-007).
Penicillins are one type of the most important antibiotics used in the clinic.Control of drug impurity profiles is an important part of ensuring drug safety.This is particularly important in penicillins where polymeri...
This study was supported by grants from the Science Foundation for Distinguished Young Scholars of Henan Province (No. 0312002100)the Nature Science Foundation of Henan Province (No. 0211040100).
Background Because of the pivotal role of the human leukocyte antigen (HLA) class II molecules in regulating the immune response and their extensive polymorphism, it is not surprising that particular HLA class II al...
ThisprojectwassupportedbytheNaturalScienceFoundationofHenanProvince (No 0 2 110 40 10 0 )andtheScienceFoundationforDistinguishedYoungScholarsofHenanProvince (No 0 3 12 0 0 2 10 0 )
Objective To investigate the mechanism (s) of penicillins allergic reaction. Methods The radioallergosorbent test (RAST) was used to detect 9 specific IgE antibodies, including major antigenic determinants: benzylpeni...
AIM:To assess and compare the efficacy and safety of two triple regimes:A)metronidazole,amoxicillin and omeprazole, which is still widely used in Russia,and B)azithromycin, amoxicillin and omeprazole in healing active...
Many metal ions can influence the stability, distribution and metabolic ways and hence the activity of drugs in human body. Penicillins are a sort oF β-lactam drugs which have important prospects. That some metal ion...