HYPERSENSITIVITY

作品数：156被引量：566H指数：13
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相关机构：中山大学附属第一医院首都医科大学北京市耳鼻咽喉科研究所北京医科大学更多>>
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NMDAR2B/PKA/CREB signaling pathway contributes to esophageal neuropathic pain in gastroesophageal reflux disease
《World Journal of Gastroenterology》2025年第11期100-117,共18页Yi Wang Guan-Wu Li Sheng-Liang Zhu Ting-Ting Xu Yi-Wen Qin Chuan-Qi Cheng Qin-Wei Zheng Cong He Bing-Duo Zhou Sheng-Quan Fang 
Supported by the National Major Project of Science and Technology for the Prevention and Control of the"Four Major Chronic Diseases",No.2024ZD0520903;National Natural Science Foundation of China,No.82004324;the Training Program for High-caliber Talents of Clinical Research at Affiliated Hospitals of SHUTCM;the Training Project for Xinglin Young and Middle-Aged Talents of Shanghai University of Traditional Chinese Medicine,No.SHUTCM HR(2020)23;the Project of National Famous Traditional Chinese Medicine Expert(Shengliang Zhu)Inheritance Studio,No.NATCM HR(2022)75;the Zhu Shengliang Academic Experience Research Studio Project of Shanghai Famous Traditional Chinese Medicine,No.SHGZS-202203;the Shanghai High-Level Talent Leadership Plan for Traditional Chinese Medicine,No.ZY(2021-2023)-0403.
BACKGROUND Esophageal hypersensitivity is an important cause of refractory gastroesophageal reflux disease,in which patients do not respond to standard acid-suppressive therapy and suffer from continuous noncardiac ch...
关键词：Gastroesophageal reflux disease Esophageal hypersensitivity N-METHYL-D-ASPARTATE Brain-derived neurotrophic factor 
A Hypersensitive,Fast-response Biomimetic Pressure Sensor Inspired by the Superior Sensing Structures of the Dragonfly's Neck
《Journal of Bionic Engineering》2025年第1期251-261,共11页Yuechun Ding Rui Zhou Changchao Zhang Hanliang Ding Bowei Li Bo Li Honglie Song Shichao Niu Junqiu Zhang Zhiwu Han Luquan Ren 
supported by the Foundation for Innovative Research Groups of the National Natural Science Foundation of China(No.52021003);National Natural Science Foundation of China(Nos.52222509,52105301);the Natural Science Foundation of Jilin Province(Grant No.20220101220JC);supported by“Fundamental Research Funds for the Central Universities”.
Flexible piezoresistive pressure sensors have attracted much attention for applications in health monitoring and human-machine interfaces due to their simple device structures and easy-to-read signals.For practical ap...
关键词：Bionic Dragonfly neck HYPERSENSITIVITY Fast response Pressure sensor 
Electroacupuncture alleviates zymosan-induced colorectal hypersensitivity
《Journal of Traditional Chinese Medicine》2025年第1期32-38,共7页LI Siting WANG Shaojun YIN Yehui DE Gejing LI Caicai WANG Ziyan CAO Wenjie 
the National Natural Science Foundation of China(No.81373724,Transient Potential Vanilloid Receptor1 Participates In The Mechanism Of Acupuncture Alleviating Visceral Hypersensitivity);the Joint Innovation Funds of China Academy of Chinese Medical Sciences(No.ZJYB2021-06,Clinical observation of acupuncture in the treatment of chronic urticaria)。
OBJECTIVE:this study to investigate the mechanism underlying the electroacupuncture(EA)alleviates colorectal hypersensitivity,a feature of irritable bowel syndrome(IBS).METHODS:The colorectal hypersensitivity model wa...
关键词：ELECTROACUPUNCTURE colorectal hypersensitivity transient receptor potential channels nerve growth factor substance P protein kinase C gamma 
Bioinspired mineral-in-shell nanoarchitectonics:Functional empowerment of mineral precursors for guiding intradentinal mineralization被引量：1
《Nano Research》2024年第5期4338-4349,共12页Xiaoran Zheng Yang Liu Mingjing Li Yuyan Li Wanshan Gao Rongmin Qiu Jiaqi Xing Jiaojiao Yang Yantao Chen Xinyuan Xu Mingming Ding Jun Luo Jianshu Li 
support provided by the National Natural Science Foundation of China(Nos.52273135,51925304,52203180).
Effective mineralization of biological structures poses a significant challenge in hard tissue engineering as it necessitates overcoming geometric complexities and multistep biomineralization processes.In this regard,...
关键词：mineral-in-shell NANOHYBRIDS self-assembly BIOMINERALIZATION dentinal tubule occlusion dental hypersensitivity 
Mechanobiology of Type 1 hypersensitivity:Elucidating the impacts of mechanical forces in allergic reactions被引量：1
《Mechanobiology in Medicine》2024年第1期48-56,共9页Henry Sutanto 
Type 1 hypersensitivity involves an exaggerated immune reaction triggered by allergen exposure,leading to rapid release of inflammatory mediators.Meanwhile,mechanobiology explores how physical forces influence cellula...
关键词：Type 1 hypersensitivity MECHANOBIOLOGY MECHANOSENSING MECHANOTRANSDUCTION ALLERGY 
A Selective‑Response Hypersensitive Bio‑Inspired Strain Sensor Enabled by Hysteresis Effect and Parallel Through‑Slits Structures
《Nano-Micro Letters》2024年第2期139-153,共15页Qun Wang Zhongwen Yao Changchao Zhang Honglie Song Hanliang Ding Bo Li Shichao Niu Xinguan Huang Chuanhai Chen Zhiwu Han Luquan Ren 
This work was supported by the Foundation for Innovative Research Groups of the National Natural Science Foundation of China(Grant No.52021003);National Natural Science Foundation of China(Grant No.51835006);the National Natural Science Foundation of China(Grant Nos.52222509,52105301,U19A20103);Jilin University Science and Technology Innovative Research Team(Grant No.2020TD-03);Interdisciplinary Integration and Innovation Project of JLU(Grant No.JLUXKJC2021ZZ03);the Natural Science Foundation of Jilin Province(Grant No.20220101220JC);Education Department of Jilin Province(Grant No.JJKH20220979KJ);Graduate Innovation Fund of Jilin University(2023CX077);supported by“Fundamental Research Funds for the Central Universities.”。
Flexible strain sensors are promising in sensing minuscule mechanical signals,and thereby widely used in various advanced fields.However,the effective integration of hypersensitivity and highly selective response into...
关键词：Bio-inspired strain sensors Hysteresis effect HYPERSENSITIVITY Selective frequency response Health monitoring applications 
Hyperactivity of the Lateral Septum Leads to Hypersensitivity in Susceptible Mice
《Neuroscience Bulletin》2023年第9期1466-1468,共3页Fan Qian Xia Zhang Bin Zhang Jie Li 
This highlight article was supported by the National Natural Science Foundation of China(32100792 and 32200825);the Shandong Natural Science Foundation(ZR202111040168);the Zhejiang Natural Science Foundation(LQ21C090003).
Everyone needs social interactions,not only humans but also most species.Positive social interaction feedback is a reward,promoting more social behaviors and acting as a stress buffer.On the contrary,negative social i...
关键词：STRESS illness contrary 
The salt-activated CBF1/CBF2/CBF3-GALS1 module fine-tunes galactan-induced salt hypersensitivity in Arabidopsis被引量：4
《Journal of Integrative Plant Biology》2023年第8期1904-1917,共14页Jingwei Yan Ya Liu Jiawen Yan Zhihui Liu Heqiang Lou Jiasheng Wu 
supported by grants from the National Natural Science Foundation of China(32001445)。
Plant growth and development are significantly hampered in saline environments,limiting agricultural productivity.Thus,it is crucial to unravel the mechanism underlying plant responses to salt stress.β-1,4-Galactan(g...
关键词：Arabidopsis thaliana BPC1/BPC2 CBF1/CBF2/CBF3 β-1 4-galactan GALS1 salt stress 
A single-center retrospective study on epidemiological and Traditional Chinese Medicine syndrome characteristics of 21010 patients with reflux/heartburn symptoms被引量：3
《Journal of Traditional Chinese Medicine》2023年第3期574-581,共8页TANG Yanping LI Peicai LIU Xi LIU Lei GONG Yanxia WEI Xiaodong LIU Lina YANG Li 
Supported by the National Natural Science Foundation of China:the Study of Mucosa Repair Mechanism of Reflux Esophagitis Cure by the Method of Huoxuetongjiang(No.81573737);Mechanism of Huoxue Tongjiang Formula Treat Reflux Esophagitis based on the Effect of Esophageal Microbiome on TLR4/PAR2/TRPV1 Pathway(No.82074213)。
OBJECTIVE:To provide a basis for the clinical identification of true and false reflux,integrated traditional Chinese and Western medicine,and psychosomatic treatment,we conducted a retrospective study of the etiology ...
关键词：gastroesophageal reflux ESOPHAGITIS PEPTIC HYPERSENSITIVITY HEARTBURN proton pump inhibitors emotional disorders syndrome complex 
Allergy identification for neurosurgical patients:updates for management
《Clinical Research Communications》2023年第2期10-20,共11页Annika Liu Xuban Palau Villarreal Brandon Lucke-Wold 
Allergic reactions in neurosurgical procedures are uncommon,but they are detrimental to a patient’s prognosis and recovery.By synthesizing data collected from other surgical fields,possible triggers and alternatives ...
关键词：ALLERGY HYPERSENSITIVITY NEUROSURGERY SCREENING prevention 
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