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The authors declare that in the article[1]published in vol.135,issue 24 of the Chinese Medical Journal,the denition about“The administration of both amoxicillin(≥3.0 g/day,1.0 t.i.d.,or 0.75 q.i.d.)and PPIs(esomepra...
supported by National Natural Science Foundation of China(No.82200607);Guangdong Basic and Applied Basic Research Foundation(Nos.2020A1515110109,2021A1515012194,2023A1515030064);Basic and Applied Research Project of Guangzhou Municipal Science and Technology Project(No.202201020631);Guangzhou Medical Key Disciplines and Specialties(No.011006003);Guangzhou Key Laboratory of Pediatric Inflammatory Bowel Disease(No.2023A03J0866);National Health Commission Key Laboratory of Tropical Disease Prevention and Control(2022NHCTDCKFKT21001).
Helicobacter pylori is a risk factor for the development of peptic ulcers with autophagy dysfunction.Omeprazole was widely known as the first-line regimen for H.pylori-associated gastritis.Objectives:The objective of ...
Objective:To investigate the therapeutic effect of omeprazole+amoxicillin in patients with gastric ulcers.Methods:62 cases of patients with gastric ulcers who were treated from January 2022 to December 2022 were recru...
Objective: to evaluate the effect of omeprazole plus amoxicillin in the treatment of gastric ulcer. Methods: 94 patients with gastric ulcer were randomly divided into single-drug group and combined group under the sam...
This research was supported by grants from the National Natural Science Foundation of China(81973363 and 82125036);the State Key Laboratory of Natural Medicines of China Pharmaceutical University(SKLNMZZCX202015);the Jiangsu Association for Science and Technology"Yong Talent Support Project";the Fundamental Research Funds for the Central Universities.
Omeprazole is a proton pump inhibitor that has recently been reported to exhibit anticancer activity against several types of cancer.However,the anticancer mechanisms of omeprazole remain elusive.Snail is an oncogenic...
Objective: to compare and analyze the pharmacological effects, therapeutic effects and drug safety of different proton pump inhibitors (PPI) in the treatment of gastric ulcer patients. Methods: according to the random...
Objective: to compare the clinical efficacy of esomeprazole and omeprazole in treating gastric ulcer. Methods: a total of 80 patients with gastric ulcer in our hospital from October 2019 to September 2021 were selecte...
Objective: to analyze the clinical effect of Kangfuxin Solution combined with omeprazole in the treatment of active gastric ulcer. Methods: 60 patients with active gastric ulcer were randomly divided into the same num...
Objective: to evaluate the efficacy of mosapride + omeprazole in the treatment of senile reflux esophagitis. Methods: From June 2019 to June 2020, 80 cases were counted. The subjects of the study were the elderly pati...
financial support from National Key R&D Program of China(2020YFE0201700);Major New Drugs Innovation and Development(2017ZX09101001-005,China);the National Natural Science Foundation of China(81803441,81803446 and 81773645);Youth Innovation Promotion Association CAS(2018323,China)。
Changes in structure of oral solid dosage forms(OSDF) elementally determine the drug release and its therapeutic effects.In this research,synchrotron radiation X-ray micro-computed tomography was utilized to visualize...