Objective:To observe the clinical effect of emergency interventional therapy for patients with acute severe non-variceal upper gastrointestinal bleeding.Methods:78 patients with acute severe non-variceal upper gastroi...
This study is registered at ClinicalTrials.gov.The registration identification number is NCT03736369。
BACKGROUND Fexuprazan,a novel potassium-competitive acid blocker,reversibly suppresses the K+/H+-ATPase enzyme in proton pumps within gastric parietal cells.Fexuprazan’s suppression of gastric acid was maintained in ...
Objective: to summarize the implementation effect of esomeprazole and the effect of effective treatment on the patient's serum index. Methods: in January of 2019 to December of this year, 98 patients coming to our hos...
BACKGROUND The pharmacokinetics and bioequivalence of esomeprazole in healthy Chinese subjects and the effects of food on the pharmacokinetics have not been well studied.AIM To evaluate the pharmacokinetic characteris...
National Natural Science Foundation of China;grant number 81900535
Esomeprazole,one of the proton pump inhibitors(PPIs),has been widely used in acid-related diseases,such as gastro-esophageal reflux disease and Helicobacter pylori infection.Compared with other PPIs,esomeprazole has h...
Supported by Shandong Provincial Medical and Health Technology Development Project,No.2014ws0020
BACKGROUND Reflux esophagitis(RE) is a common digestive disorder, and its frequent recurrences cause significant physical pain and are financially burdensome to patients. However, studies on the natural history of tre...
Objective To investigate the clinical effect of esomeprazole combined with magnesium aluminum carbonate in patients with gastric ulcer. Methods A total of 106 patients with gastric ulcer who were treated in our hospit...
Supported by Research Foundation of Chang Gung Memorial Hospital,No.CMRPG8D1441
AIM To compare the one-week clinical effects of single doses of dexlansoprazole and esomeprazole on grades A and B erosive esophagitis.METHODS We enrolled 175 adult patients with gastroesophageal reflux disease(GERD)....
AIM To evaluate the effectiveness of oral esomeprazole(EPZ) vs injectable omeprazole(OPZ) therapy to prevent hemorrhage after endoscopic submucosal dissection(ESD).METHODS A case-control study was conducted using a qu...