supported by National Natural Science Foundation of China(No.82200607);Guangdong Basic and Applied Basic Research Foundation(Nos.2020A1515110109,2021A1515012194,2023A1515030064);Basic and Applied Research Project of Guangzhou Municipal Science and Technology Project(No.202201020631);Guangzhou Medical Key Disciplines and Specialties(No.011006003);Guangzhou Key Laboratory of Pediatric Inflammatory Bowel Disease(No.2023A03J0866);National Health Commission Key Laboratory of Tropical Disease Prevention and Control(2022NHCTDCKFKT21001).
Helicobacter pylori is a risk factor for the development of peptic ulcers with autophagy dysfunction.Omeprazole was widely known as the first-line regimen for H.pylori-associated gastritis.Objectives:The objective of ...
Introduction: During the pharmacological stress test with dipyridamole, a normal hemodynamic response is slightly reduced blood pressure and raised heart rate (HR). However, sometimes the HR response is reduced. This ...
National Key R&D Program of China(2017YFB0202600 and 2020YFC0841400);National Natural Science Foundation of China(91742109,8152204,31770978,81773674,and 21877134);National Health&Medical Research of Australia(1080321,1143976 and 1150425);Science Foundation of Guangzhou City(201904020023,China);Guangdong Province Higher Vocational Colleges and Schools Pearl River Scholar Funded Scheme(2016 and 2019,China);Guangdong Provincial Key Laboratory of Construction Foundation(2017B030314030,China);Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program(2017BT01Y093,China);Zhejiang University special scientific research fund for COVID-19 prevention and control(China);National Health&Medical Research of Australia(1080321,1143976,and 1150425);Taikang Insurance Group Co.,Ltd.;Beijing Taikang Yicai Foundation(Beijing,China)
Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection can cause acute respiratory distress syndrome,hypercoagulability,hypertension,and multiorgan dysfunction.Effective antivirals with safe clinical pro...
Herbal bioactives have been shown to influence the pathogenesis of homocysteine associated vascular complications.However,there are no simple cellular models to study their role in preventing angiogenesis impairment b...
Lumbar sympathetic block is an analgesic procedure frequently performed in chronic pain clinics for ischemic lower limb pain from peripheral arterial disease. Although the lumbar sympathetic ganglia are anatomically n...
有效避免二次卒中预防方案(Prevention Regimen for Effectively Avoiding Second Strokes,PROFESS)试验是迄今规模最大的一项卒中二级预防研究,它对缓释型双嘧达莫+阿司匹林(extended-release dipyridamole plusaspirin,eDYP-AS...
Objective: It was known that neutrophils play an important role in ischemic-reperfusion injury. In this study we tested the effect and its mechanism of dipyfidamole on neutrophils. Methods:Hydrogen peroxide(H2O2) ...
A novel floating osmotic pump controlled release system (FOP) and traditional matrix sustained release tablets (MT) of dipyridamole (DIP) were characterized in terms of pharmacokinetics, drug release, and in vit...