National Nature Science Foundation of China 82471000(to K.J.);National Nature Science Foundation of China 82170978(to K.J.);National Nature Science Foundation of China 82325012(to L.N.N.);National Key Research and Development Program 2023YFC2509100(to K.J.)。
Temporomandibular joint osteoarthritis(TMJ-OA)is a common disease often accompanied by pain,seriously affecting physical and mental health of patients.Abnormal innervation at the osteochondral junction has been consid...
Supported by the National Natural Science Foundation of China,No.82400966;Guangdong Basic and Applied Basic Research Foundation,No.2021A1515111025;Science and Technology Projects in Guangzhou,No.2024A04J5170.
In this article,we review the study by Jin et al,which examined the role of intestinal glucagon-like peptide-1(GLP-1)in counterregulatory responses to hypoglycemia in patients with type 1 diabetes mellitus(T1DM).With ...
supported by the National Natural Science Foundation of China (82472439,82270935,81974337,82102627);the Hubei Provincial Natural Science Foundation of China (2021CFB095);the Wuhan Knowledge Innovation Project (2022020801020468);the Project of Scientific Research Plan of Wuhan Municipal Health Commission (WX21Q19)。
Osteonecrosis of the femoral head(ONFH)is a common complication of glucocorticoid(GC)therapy.Recent advances demonstrate that sympathetic nerves regulate bone homeostasis,and GCs lower the sympathetic tone.Here,we sho...
To the Editor:Sympathetic paraganglioma in the pericardium is rare,which can be life-threatening.It presents with symptoms,such as refractory hypertension,palpitations,and other hormone-related manifestations.
supported by the National Natural Science Foundation of China(31930061,21790394,82000757,31761133016,31821091,31330024,31171026,31327901,32171233,31670843,and 21790390);the National Key Research and Development Program of China(2016YFA0500401);the National Postdoctoral Program for Innovative Talents(BX20190012);the China Postdoctoral Science Foundation(2020M670029).
Many components in cells undergo liquid-liquid phase separation(LLPS)to form condensed granules by multivalent interactions through intrinsically disordered regions or binding partners[1].The LLPS assembly,formed by c...
Supported by the National Natural Science Foundation of China(No.82004461);Medical Research Project of Sichuan Province(No.S21099);the First Affiliated Hospital of Chengdu Medical College(No.CYFY2021ZD05,No.CYFY-GQ27);Chengdu Medical College(No.CYZZD20-03,No.202013705082)。
Objective:To investigate whether electroacupuncture(EA) at sensitized acupoints could reduce sympathetic-sensory coupling(SSC) and neurogenic inflammatory response by interfering with 5-hydroxytryptamine(5-HT)ergic ne...
This study was funded by the Key Scientific Research Project Plan of Higher Education Institutions in Henan Province (Number:23A320025);by the China International Medical Exchange Foundation 2021 Cardiovascular Multidisciplinary Integrated Thinking Research Fund (Number:z-2016-23-2101-37)。
The onset of cardiac arrest (CA) is sudden and critical.Due to cerebral ischaemia and hypoxia, the prognosis for post-cardiopulmonary resuscitation (CPR) patients is poor. Paroxysmal sympathetic hyperexcitability (PSH...
supported by grants from the National Natural Science Foundation of China(82072526,82171212,and 81870867).
Brachial plexus avulsion(BPA)is a combined injury involving the central and peripheral nervous systems.Patients with BPA often experience severe neuropathic pain(NP)in the affected limb.NP is insensitive to the existi...
To define the systemic neuroimmune interactions in health and disease,we recently suggested immunoception as a term that refers to the existence of bidirectional functional loops between the brain and the immune syste...
This work was supported by NIH Grants NS045594 and NS113243.
Although sympathetic blockade is clinically used to treat pain,the underlying mechanisms remain unclear.We developed a localized microsympathectomy(mSYMPX),by cutting the grey rami entering the spinal nerves near the ...