云南高校图书馆联盟文献共享服务平台- ANTIPLATELET

ANTIPLATELET: 作品数：112被引量：281H指数：9; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：胡琨朱元军王银叶刘晓岩邹建军更多>>; 相关机构：广东省人民医院(广东省医学科学院)北京大学玉溪师范学院莆田学院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家科技支撑计划广东省自然科学基金国家重点基础研究发展计划更多>>

Real-time platelet P2Y_(12) receptor occupancy as a promising pharmacodynamics biomarker for bridging the gap between PK/PD of clopidogrel therapy: 《Acta Pharmaceutica Sinica B》2025年第1期484-493,共10页Haipeng Li Yueming Gu Yumeng Zhao Aiyun Xu Dong Sun Jingkai Gu; supported by the Scientific and Technological Development Plan of Jilin Province China(Grant No.20210204068YY).; Clopidogrel effectively inhibits platelet aggregation in response to ADP by irreversibly binding to the platelet P2Y_(12) receptor through its active metabolite.However,the observed discrepancies between the pharmacok...; 关键词：CLOPIDOGREL P2Y_(12) ANTIPLATELET Real-time receptor occupancy PDbiomarker

Protective effects of long term antiplatelet and anticoagulant therapy in hospitalized patients with inflammatory bowel disease: 《World Journal of Gastrointestinal Pharmacology and Therapeutics》2024年第6期28-38,共11页Madhav Changela Sagar Pandey Janak Bahirwani Nishit Patel Maulik Kaneriya Sanket D Basida Anish Shah Rahul Thakur Krishna Bodrya Suruchi Jai Kumar Ahuja Yecheskel Schneider; BACKGROUND Inflammatory bowel disease(IBD),with its rising prevalence rates is associated with an increased risk of cardiovascular and thromboembolic events.Antiplatelets and/or anticoagulants agents are often prescri...; 关键词：Inflammatory bowel disease ANTICOAGULATION Antiplatelet therapy Healthcare utilization MORTALITY

Spontaneous Coronary Artery Disease in a Healthy Fibromuscular Dysplasia Patient: A Case Report: 《Case Reports in Clinical Medicine》2024年第9期375-381,共7页Munir Shunnar Obada Alshaikh Maha Alzubaidi Hyun-Ryung Choi; Our case is a 72-year-old female with Fibromuscular Dysplasia (FMD) presented to the Emergency Department (ED) with acute coronary syndrome (ACS), more specifically NSTEMI. In ED, troponin levels were elevated and non...; 关键词：SCAD NSTEMI STEMI ACS Eliquis PSEUDOANEURYSM Fibromuscular Dysplasia ANTICOAGULANT ANTIPLATELET Coronary Dissection Neuroendovascular Cardiology WARFARIN Cath Lab APIXABAN Clopidogrel

Prognostic Analysis and an Appropriate Antiplatelet Strategy for Patients With Percutaneous Coronary Intervention and High Bleeding Risk:Rationale and Protocol for a MultiCenter Cohort Study: 《Cardiology Discovery》2024年第3期213-220,共8页Junyan Zhang Zhongxiu Chen Hua Wang Mian Wang Chen Li Sen He Yong Peng Jiafu Wei Yong He; supported by the 1-3-5 project for disciplines of excellence—Clinical Research Incubation Project,West China Hospital,Sichuan University(2019HXFH059 and 2021HXFH021);the Natural Science Foundation of China(82100282).; Percutaneous coronary intervention(PCI)is an important treatment strategy for patients with coronary artery disease.However,bleeding after PCI significantly increases the mortality risk.The search for prognostic predi...; 关键词：Percutaneous coronary intervention High bleeding risk Dual antiplatelet therapy

Distribution of gene polymorphisms associated with aspirin antiplatelet in the Han NSTEMI population: 《Journal of Hainan Medical University》2024年第2期20-25,共6页LI Liu-shui WANG Fei ZHOU Ao YANG Qing LIU Xian-jun; Capital Clinical Characteristic Application Research Project(No.Z181100001718144);Beijing Tongzhou District Science and Technology Plan Project(No.KJ2017CX036-06);In-hospital Project of Shanghai Jinshan District Integrated Traditional Chinese and Western Medicine Hospital(No.2022-1)。; Objective:To analyze the genotype and allele distribution characteristics of GPⅢa PLA2(rs5918),PEAR1(rs12041331),and PTGS1(rs10306114)genes related to the antiplatelet pharmacological effects of aspirin,providing ref...; 关键词：ASPIRIN ANTIPLATELET Non-ST-segment elevation myocardial INFARCTION Gene polymorphism Genotype distribution

Efficacy and safety of different dual antiplatelet strategies in patients undergoing percutaneous coronary intervention:A systematic review and network meta-analysis: 《Chronic Diseases and Translational Medicine》2023年第4期299-308,共10页Yuttana Wongsalap Kirati Kengkla Preyanate Wilairat Khemanat Ratworawong Surasak Saokaew Chaisiri Wanlapakorn; Thailand Science Research and Innovation fund;Universityof Phayao,Grant/Award Numbers:UoE66003,FF65-RIM100;Unit of Excellence on Clinical Outcomes Research and IntegratioN(UNICORN)。; Background:Dual antiplatelet therapy(DAPT)is key for preventing ischaemic events post-percutaneous coronary intervention(PCI).Various DAPT modifications like the shortened duration or P2Y12 inhibitor(P2Y12i)de-escalat...; 关键词：DE-ESCALATION percutaneous coronary intervention short dual antiplatelet therapy

Progress in the study of antiplatelet and antithrombotic effects of salvia polyphenolic acid for injection被引量：1: 《Drug Combination Therapy》2022年第4期1-7,共7页Lei Fan Du-Hong Xie Yan Zhou Bo-Xuan Zhao Xiao-Ying Han De-Kun Li Ai-Chun Ju Xin-Yu Zhang Wen-Zhe Wang Chang-Xiao Liu Wen-Yuan Gao; supported by the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(No.ZYYCXTD-D-202005);the Key Project at Central Government Level(No.2060302);the Special Project for Transformation of Scientific and Technological Achievements in Qinghai Province(No.2021-SF-150).; Salvia polyphenolic acid for injection is a new generation of Chinese medicine injectable,which is developed by extracting and separating the water-soluble phenolic acid active ingredients of Salvia divinorum by using...; 关键词：salvia polyphenolic acid for injection oxidative stress CARDIOMYOPATHY THROMBOSIS anti-inflammator apoptosis

Rumex acetosella Inhibits Platelet Function via Impaired MAPK and Phosphoinositide 3-Kinase Signaling: 《Chinese Journal of Integrative Medicine》2022年第9期802-808,共7页Bo-Ra Jeon Muhammad Irfan Seung Eun Lee Jeong Hoon Lee Man Hee Rhee; Supported by a grant of National Research Foundation of Korea(No.2018R1D1A1A09083797)。; Objective:To examine the antiplatelet and antithrombotic activity of Rumex acetosella extract.Methods:Standard light aggregometry was used for platelet aggregation,intracellular calcium mobilization assessed using Fur...; 关键词：ANTIPLATELET ETHNOMEDICINE integrinα_(Ⅱb)β_(3) mitogen-activated protein kinase Rumex acetosella L.

Research on Emergency Treatment of Acute ST-segment Elevation Myocardial Infarction: 《外文科技期刊数据库(文摘版)医药卫生》2022年第5期168-171,共4页WANGLi; Objective: to explore the therapeutic effect and effect of antiplatelet intervention on patients with ST-segment elevation acute myocardial infarction in pre-hospital first aid. Methods: 100 patients with ST-segment e...; 关键词：ANTIPLATELET pre hospital first aid ST segment elevation acute myocardial infarction

Association between antiplatelet medication and cerebral microbleeds in stroke-free population被引量：2: 《Journal of Geriatric Cardiology》2022年第6期409-417,共9页Miao-Xin YU Ya-Nan JIA Dan-Dan YANG Run-Hua ZHANG Yong JIANG Gui-Tao ZHANG Hui-Yu QIAO Hua-Lu HAN Rui SHEN Zi-Han NING Xi-Hai ZHAO Gai-Fen LIU Yong-Jun WANG; supported by the National Key Research and Development Program of the Ministry of Science and Technology of China(2017YFC 1307702);the Capital’s Funds for Health Improvement and Research(No.2020-1-2041).; BACKGROUND Cerebral microbleeds(CMBs)may increase the risk of future intracerebral hemorrhage and ischemic stroke.However,It is unclear whether antiplatelet medication is associated with CMBs.This study aimed to inves...; 关键词：MEDICATION 3.0T ANTIPLATELET

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