CLOPIDOGREL

作品数:154被引量:581H指数:15
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相关领域:医药卫生更多>>
相关作者:邹建军邱声强张冰胡正刚王庄更多>>
相关机构:南京医科大学中国药科大学湖州市中心医院太原市中心医院更多>>
相关期刊:更多>>
相关基金:国家自然科学基金国家科技支撑计划国家重点基础研究发展计划河北省自然科学基金更多>>
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Trends in dual antiplatelet therapy regimens and clinical outcomes among patients with acute coronary syndrome undergoing percutaneous coronary intervention with drug-eluting stents: A multicenter real-world study
《Chronic Diseases and Translational Medicine》2025年第1期57-68,共12页Preyanate Wilairat Arintaya Phrommintikul Thanyalak Chotayaporn Supharat Wattanasombat Rungtiwa Hmuenpha Supitchaya Kornjirakasemsan Duangkamon Poolpun Voratima Yoodee 
The Ajarn Kasem Pangsriwong Foundation supported the research project;Pharmaceutical Care Training Center(PCTC)at the Faculty of Pharmacy,Chiang Mai University。
Background:The patterns of dual antiplatelet therapy(DAPT)use and the associated clinical outcomes in current practice remain limited.This study evaluates DAPT regimen patterns and clinical outcomes among acute corona...
关键词:acute coronary syndrome CLOPIDOGREL dual antiplatelet therapy percutaneous coronary intervention PRASUGREL prescription pattern ticagrelor 
Efficacy and Safety of Dual Antiplatelet Therapy in High-Risk, Post-Percutaneous Coronary Intervention Patients beyond One Year
《World Journal of Cardiovascular Diseases》2025年第2期117-126,共10页Avinash Singh Rupesh Sinha Mahim Saran Danish Kazmi Himanshu Gupta Ganesh Seth 
Background: Individuals with coronary artery disease (CAD) who have undergone a percutaneous coronary intervention (PCI) are at an increased risk for adverse coronary events. Management with dual antiplatelet therapy ...
关键词:ASPIRIN Clopidogrel Drug-Eluting Stents Dual Antiplatelet Therapy Percutaneous Coronary Intervention 
Real-time platelet P2Y_(12) receptor occupancy as a promising pharmacodynamics biomarker for bridging the gap between PK/PD of clopidogrel therapy
《Acta Pharmaceutica Sinica B》2025年第1期484-493,共10页Haipeng Li Yueming Gu Yumeng Zhao Aiyun Xu Dong Sun Jingkai Gu 
supported by the Scientific and Technological Development Plan of Jilin Province China(Grant No.20210204068YY).
Clopidogrel effectively inhibits platelet aggregation in response to ADP by irreversibly binding to the platelet P2Y_(12) receptor through its active metabolite.However,the observed discrepancies between the pharmacok...
关键词:CLOPIDOGREL P2Y_(12) ANTIPLATELET Real-time receptor occupancy PDbiomarker 
In-hospital outcomes of anemic patients with acute coronary syndrome receiving ticagrelor versus clopidogrel: Results of the Chinese Cardiovascular Care Improvement (CCC)-Acute Coronary Syndrome Project
《Chinese Medical Journal》2024年第20期2489-2491,共3页Zhiqiang Zhang Yasong Wang Jun Wang Xiaofan Cao Miaohan Qiu Xiaoxiang Tian Yaling Han Xiaozeng Wang 
This study was supported by the China National Key R&D Project (contract No. 2022YFC2503500);The CCC-ACS project is a program of the AHA and the CSC. The AHA received funding from Pfizer through an independent grant for learning and change and Astra-Zeneca as a quality improvement initiative.
To the Editor:Dual antiplatelet therapy(DAPT),which comprises aspirin plus a P2Y12 receptor inhibitor,is the standard approach for reducing cardiac and systemic ischemic events in individuals with coronary artery dise...
关键词:coronary PATIENTS BLEEDING 
Analysis of the Effectiveness of Clopidogrel Combined with Aspirin in the Treatment of Coronary Heart Disease in Community-Dwelling Elderly
《Journal of Clinical and Nursing Research》2024年第3期114-119,共6页Wenling Wang 
Objective:To analyze the combined therapeutic effect of clopidogrel(CLO)and aspirin(ASP)on coronary heart disease(CHD)in community-dwelling elderly.Methods:Thirty elderly patients with CHD who were admitted to the Xin...
关键词:CLOPIDOGREL ASPIRIN Coronary heart disease in the elderly in the community Adverse reactions Quality of life 
Low RBC counts predict high on-treatment platelet reactivity in patients undergoing percutaneous coronary intervention and treated with clopidogrel
《The Journal of Biomedical Research》2024年第1期87-91,共5页Qian Gu Qin Wang Rui Hua Wenhao Zhang Jianzhen Teng Jiazheng Ma Zhou Dong Xiaoxuan Gong Chunjian Li 
supported by the National Natural Science Foundation of China(Grant No.82170351);the Jiangsu Province's Key Provincial Talents Program(Grant No.ZDRCA2016013);the Special Fund for Key R&D Plans(Social Development)of Jiangsu Province(Grant No.BE2019754).
Dear Editor,Cardiovascular disease is the leading cause of deaths worldwide,with coronary artery disease(CAD)accounting for approximately 50%of its mortality.Dual antiplatelet therapy,including aspirin and a P2Y12 inh...
关键词:CORONARY PATIENTS mortality 
Effect of cytochrome P4502C19(CYP2C19)gene polymorphism and clopidogrel reactivity on long term prognosis of patients with coronary heart disease after PCI
《Journal of Geriatric Cardiology》2024年第1期90-103,共14页Cheng-Yan HU Yan-Ling WANG Zhen-Xing FAN Xi-Peng SUN Shuai WANG Zhi LIU 
supported by the National Natural Science Foundation of China(No.62172288).
Objective To investigate the impact of CYP2C19 gene polymorphism on clopidogrel reactivity and its association with longterm clinical outcome in patients with coronary heart disease(CHD)undergoing percutaneous coronar...
关键词:CYP2C19 DRUGS PCI 
Proton pump inhibitors and gastroprotection in patients treated with antithrombotic drugs: A cardiologic point of view
《World Journal of Cardiology》2023年第8期375-394,共20页Maurizio Giuseppe Abrignani Alberto Lombardo Annabella Braschi Nicolo Renda Vincenzo Abrignani 
Aspirin,other antiplatelet agents,and anticoagulant drugs are used across a wide spectrum of cardiovascular and cerebrovascular diseases.A concomitant proton pump inhibitor(PPI)treatment is often prescribed in these p...
关键词:Antithrombotic drugs ANTICOAGULANTS ASPIRIN CLOPIDOGREL Gastrointestinal bleeding Proton pump inhibitors 
Risk of ischaemic and haemorrhagic stroke in Chinese undergoing percutaneous coronary intervention treated with potent P2Y12 inhibitor versus clopidogrel被引量:1
《Stroke & Vascular Neurology》2022年第4期310-318,I0015-I0019,共14页Andrew Kei-Yan Ng Pauline Yeung Ng April Ip Kui Kai Lau Chung-Wah Siu 
Background Stroke after acute coronary syndrome(ACS)can be devastating.It is uncertain whether the risks of ischaemic stroke or intracranial haemorrhage(ICH)are associated with different choices of P2Y12 inhibitors(po...
关键词:P2Y12 CORONARY haemorrhagic 
Analysis on the Effect of Clinical Drugs on Angina Pectoris in Cardiovascular Department
《外文科技期刊数据库(文摘版)医药卫生》2022年第10期014-017,共4页ZHANGQinbao 
Objective: to analyze the value of medical intervention on angina pectoris in cardiovascular department. Methods: 80 patients were selected from January 2019 to February 2021 for analysis within the time range of the ...
关键词:cardiovascular medicine angina pectoris clinical medicine CLOPIDOGREL curative effect 
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