BENZYL

作品数:201被引量:347H指数:9
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相关领域:理学医药卫生更多>>
相关作者:钱家庆韩瑜周雯王霞兰燕宇更多>>
相关机构:上海交通大学绵阳市中心医院华西医科大学附属一医院华中科技大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划北京市自然科学基金更多>>
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N-Benzyl arylamide derivatives as novel and potent tubulin polymerization inhibitors against gastric cancers:Design,structure-activity relationships and biological evaluations
《Chinese Chemical Letters》2025年第2期228-233,共6页Jian Song Shenghui Wang Qiuge Liu Xiao Wang Shuo Yuan Hongmin Liu Saiyang Zhang 
supported by the National Natural Science Foundation of China(Nos.82273782 and U2004123);Training Program for Young Key Teachers of Colleges and Universities in Henan Province(No.2023GGJS008)。
In this work,we employed a ring-opening strategy to develop a series of novel N-benzyl arylamide derivatives as tubulin polymerization inhibitors.Notably,13n(MY-1388)exhibited remarkable antiproliferative potency on f...
关键词:TUBULIN Colchicine binding site CA-4 N-Benzyl arylamide Antiproliferative activities 
Chlorination of benzyl group on the terminal unit of A_(2)-A_1-D-A_1-A_(2) type nonfullerene acceptor for high-voltage organic solar cells
《Chinese Chemical Letters》2025年第1期312-317,共6页Jinge Zhu Ailing Tang Leyi Tang Peiqing Cong Chao Li Qing Guo Zongtao Wang Xiaoru Xu Jiang Wu Erjun Zhou 
support from the National Natural Science Foundation of China(Nos.52373176,52073067)。
Benzotriazole(BTA)-based A_(2)-A_1-D-A_1-A_(2)type wide-bandgap(WBG)non-fullerene acceptors(NFAs)have shown promising potential in indoor photovoltaic,and in-depth investigation of their structure-property relationshi...
关键词:High open-circuit voltage BENZOTRIAZOLE Non-fullerene acceptor Terminal engineering CHLORINATION 
Reactions of Alkynyl Aryl Phosphine Oxide with Oxalyl Bromide
《有机化学》2024年第12期3753-3760,共8页Zhao Peng Gan Zhenjie Li Zhuo Wang Lili Duan Zheng 
国家自然科学基金(Nos.22101262,22171245);河南省科技攻关(No.242102230166)资助项目.
Tertiary phosphines and their oxides react with oxalyl bromide to generate corresponding quaternary phosphonium salts,which can be further transformed as active intermediates to facilitate the bromination of alcohols ...
关键词:aryl phosphine oxide benzyl phosphine oxide oxalyl bromide quaternary phosphonium salt ALKYNE 
Cobalt-manganese bimetallic organic frameworks catalyzed solvent-free oxidation of benzyl C-H bonds with O_(2) as sole oxidant
《Nano Research》2024年第11期9532-9539,共8页Ke Cao Yan Zhou Shanshan Lv Mengmeng Feng Changjin Qian Zheng Chen 
supported by the Key Research and Development Project of Anhui Province(No.2022a05020048);the Open Project of Anhui Provincial Key Laboratory for Degradation and Monitoring of Pollution of the Environment(No.FSKFKT007D);the State Key Laboratory of Heavy Oil Processing(No.SKLHOP202202007);the Excellent Youth Research Project in Universities of Anhui Province(No.2023AH030050);the University Collaborative Innovation Project of Anhui Province(No.GXXT-2023-034).
The selective oxidation of hydrocarbons can be used to produce oxygen-containing functional compounds such as alcohols, aldehydes or ketones and its efficient and green conversion lies in the development of efficient ...
关键词:metallic organic framework transition metal NANOCATALYSIS oxidation KETONE 
Multi-site anchoring lead-halide octahedral by benzylphosphonic acid to regulate phase distribution for efficient PeLEDs
《Nano Research》2024年第11期10034-10041,共8页Jiahao Tang Yifei Wang Hengyang Xiang Run Wang Kun Zhang Xinyi Lv Xinrui Chen Ziqing Xu Zhesheng Chen Lei Wang Aidi Zhang An Xie Haibo Zeng 
financially supported by the National Key Research and Development Program of China(No.2022YFB3606502);the National Natural Science Foundation of China(Nos.52131304 and 62004101).
Quasi-two-dimensional perovskite light-emitting diodes (quasi-2D PeLEDs) are emerging as high-potential candidates for new generation of wide-color gamut displays due to their simple, low-cost solution process, and hi...
关键词:quasi-2D perovskites light-emitting diodes benzylphosphonic acid phase distribution defect passivation 
t-BuOLi Catalyzed Esterification of N-Benzyl-N-Boc-amides with Carbohydrates
《有机化学》2024年第9期2924-2932,共9页Ye Danfeng Xu Bing Wan Yunhui 
宁波工程学院启动基金(No. 2130011540027)资助项目.
Based on a strategy of ground-state destabilisation of the N—C bond,a general protocol for the esterification of amides with carbohydrates was reported.This protocol offers mild reaction conditions,excellent yields,a...
关键词:t-BuOLi N-benzyl-N-Boc-amides ESTERIFICATION glycoconjugates 
Porous S-doped carbon nitride foam with accelerated charge dynamics for synchronous photocatalytic hydrogen production and highly selective oxidation of amines
《Nano Research》2024年第8期6860-6869,共10页Yu He Aiping Wu Nan Wang Ying Xie Chungui Tian Honggang Fu 
the National Key Research and Development Program of China(No.2022YFA1503003);the National Natural Science Foundation of China(Nos.U20A20250 and 22271081);the Natural Science Foundation of Heilongjiang Province(No.ZD2021B003);the University Nursing Program for Young Scholars with Creative Talents in Heilongjiang Province(No.UNPYSCT-2020004).
Photocatalytic hydrogen evolution coupled with organic oxidation holds great promise for converting solar energy into high-valueadded chemicals,but it is hampered by sluggish charge dynamics and limited redox potentia...
关键词:photocatalysis S-doped carbon nitride band structure regulation hydrogen evolution coupled with benzylamine oxidation reaction mechanism 
C-F insertion reaction sheds new light on the construction of fluorinated compounds
《Chinese Chemical Letters》2024年第8期163-169,共7页Dong-Sheng Deng Su-Qin Tang Yong-Tu Yuan Ding-Xiong Xie Zhi-Yuan Zhu Yue-Mei Huang Yun-Lin Liu 
The Tertiary Education Scientific Research Project of Guangzhou Municipal Education Bureau(No.202235305)is gratefully acnowledged for financial support.
The atom-economical C-F insertion chemistry is emerged as a promising technology for the synthesis of various fluorinated scaffolds,which have wide applications both in the academic and the industrial com-munities.The...
关键词:C-F insertion Benzyl fluoride Acyl fluoride gem-Difluorocyclopropane Fluorinated scaffold 
Efficient conversion of aromatic and phenylpropanoid alcohols to acids by the cascade biocatalysis of alcohol and aldehyde dehydrogenases
《Synthetic and Systems Biotechnology》2024年第2期187-195,共9页Zetian Qiu Xiaohui Liu Jie Yu Yushuo Zhao Guang-Rong Zhao Shengying Li Kun Liu Lei Du Li Ma 
This work was supported by the National Key Research and Development Program of China(2021YFA0911500);the National Natural Science Foundation of China(32071266,32170088,and 32370032);the Shandong Provincial Natural Science Foundation(ZR2020ZD23);the State Key Laboratory of Microbial Technology Open Projects Fund(M2022-01).
Benzyl and phenylpropanoid acids are widely used in organic synthesis of fine chemicals,such as pharmaceuticals and condiments.However,biocatalysis of these acids has received less attention than chemical synthesis.On...
关键词:Benzyl acids Phenylpropanoid acids Alcohol dehydrogenases Aldehyde dehydrogenases Whole-cell catalysis 
Evaluation of the Antibacterial and Antifungal Capacity of Nanoemulsions Loaded with Synthetic Chalcone Derivatives Di-Benzyl Cinnamaldehyde and Benzyl 4-Aminochalcone
《Journal of Renewable Materials》2024年第2期285-304,共20页Flavia Oliveira Monteiro da Silva Abreu Taysse Holanda Joice Farias do Nascimento Henety Nascimento Pinheiro Rachel Menezes Castelo Hélcio Silva dos Santos Thais Benincá Patrícia da Silva Malheiros Júlio César Sousa Prado Raquel de Oliveira Fontenelle Maria Madalena de Camargo Forte 
supported by the National Council for Scientific Development-CNPQ/MCTI/FNDCT N18/2021,by the Concession of Research Funding Grant Number 406522/2021-9-1 to F.O.M.S.Abreu.Helcio Silva dos Santos acknowledges financial support from CNPq-PQ (Grant Number 306008/2022-0).
With the increase in antimicrobial resistance,it has become necessary to explore alternative approaches for combating and preventing diseases.DB-cinnamaldehyde(CNM)and Benzyl4-amino(B4AM)are bioactive compounds derive...
关键词:Polysaccharide NANOEMULSIONS S.aureus S.minnesota CHALCONES alginate 
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