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As important natural and pharmaceutical motifs,the catalytic construction of structurally diverse 3,3-disubstituted oxindoles often requires elaborate synthetic efforts on optimizations.Herein,we developed a simple an...
financial support of National Natural Science Foundation of China(21901193,22271314 and 22377097);the innovation foundation of Key Laboratory of Green Chemical Engineering Process of Ministry of Education(GCX2023002).
Concise assembly of spirooxindoles is of great significance but a challenging task in modern organic synthesis.Described herein is an unusual base-promoted[4+2]spiroannulation of rarely used isatin-derivedβ-silylcarb...
An efficient C-3 sulfuration of oxindoles has been developed.Using disulfide as the sulfurating agent,a wide range of sulfurated oxindoles have been synthesized under t-BuOK/N,N-dimethylformamide(DMF)promoted conditio...
supported by the National Natural Science Foundation of China(No.22293011).
Herein,we report an efficient and practical protocol for the photoinduced dehalocyclization of ortho-halophenylacrylamides with formate by the engagement of a CO_(2) radical anion to access substituted oxindoles.This ...
support from the National Natural Science Foundation of China(No.22005179);the Natural Science Foundation of Shandong Province(Nos.ZR2020QB113,ZR2020MB018 and ZR2021QB049).
A general and high-efficiency C-alkylation of oxindoles and barbituric acids has been developed by a Cp*Ir complex[Cp*Ir(2,20-bpyO)(OH)]Na with a bipyridine-based functional ligand.In particular,H_(2)O was selected as...
National Natural Science Foundation of China(No.21805032);Natural Science Foundation of Shanghai,China(No.19ZR1401400);Fundamental Research Funds for the Central Universities,China(No.20D128502).
Two acceptor-donor-acceptor(A-D-A)type non-fullerene acceptors(namely WH1 and WH7)containing the oxindole-based bridge are designed and synthesized for polymer solar cells(PSCs)applications.The bridge unit is introduc...
supported by a grant from the National Nat-ural Science Foundation of China(No.21472176).
The asymmetric carbenoid C–H insertion of 3-diazooxindoles into 1,4-cyclohexadiene has been accomplished in the presence of chiral bis(imidazoline) NCN pincer iridium(Ⅲ) complexes as the catalysts. With a catalyst l...
Un der the catalysis of chiral Cu(ll)complex,C2 and C3 alkylati on of pyrrole and C3 alkylation of in dole were realized simulta neously.The chiral oxindole skeleton with an all-carb on quater nary stereogenic cen ter...
financial support by the National Natural Science Foundation of China (Nos.21878264,21971222)。
Ynamides are electron-rich alkynes with unique reactivities and act as flexible building blocks in organic synthesis.Therefore,the investigation for transformation of ynamides with exceptional selectivity and efficien...
the National Natural Science Foundation of China(No.21672027)for financial support;supported by High-Level Entrepreneurial Talent Team of Jiangsu Province(No.2017-37)。
When treated with an alkoxide base like t-BuOK in aprotic solvent,N-di phenyl methyl imino oxindoles,made conveniently through condensation of corresponding isatins with N-di phenyl methyl amine,are deprotonated to fo...