supported by the National Natural Science Foundation of China(22278200,21971095,21502080,21772019,21772076,21871117,91956203);the National Key R&D Program of China(2023YFA1506400);the Science and Technology Major Program of Gansu Province of China(22ZD6FA006,23ZDFA015);the“111”Program of Ministry of Education of China;the Major Project of the Ministry of Science and Technology of China(2018ZX09711001-005-002);the Science and Technology Commission of Shanghai Municipality(19JC1430100)。
Herein,the de novo synthesis of atropisomeric benzofurans through the Cu/spirocyclic-pyrrolidine-oxazoline(SPDO)complex catalyze asymmetric formal[3+2]cycloaddition between quinones and ynamides is explored,producing ...
support of the National Key R&D Program of China(No.2021YFF0701600),NSFC(No.22031004);the Shanghai Municipal Education Commission(No.20212308);China Postdoctoral Science Foundation(No.2022M713667)and STCSM(No.23ZR1445600).
A highly enantioselective palladium-catalyzed intramolecular Heck reaction of unactivated alkenes is developed,which provides a powerful route to access a broad range of chiral 3,3-disubstituted-2,3-dihydrobenzofurans...
Benzofuran is an essential structural component found in a wide range of natural products,agrochemicals and drugs,possessing a range of biological activities.In recent years,there have been numerous reports of success...
financial supported by the National Natural Science Foundation of China(No.21672061);National Key Research Program of China(No.2018YFD0200105);supported by Innovation Program of Shanghai Municipal Education Commission(No.201701070002E00037);the Fundamental Research Funds for the Central Universities。
Plant-parasitic nematodes are major threat for crop protection.The lack of nematicides with new mode of action and increasing resistance raises the need for novel nematicides.In order to seek new nematicidal lead,orig...
supported by National Natural Science Foundation of China(grant no.21772183);the Fundamental Research Funds for the Central Universities(grant no.WK2060190086);“1000-Youth Talents Plan”start-up funding as well as the University of Science and Technology of China.
In this paper,we developed an electrophilic ring-opening reaction,which is beyond the strained small ring system.Under reductive nickel catalysis,ring-opening of diverse benzofurans via endocyclic inert carbon–oxygen...
The authors thank the National Natural Science Foundation of China(21462038);Key Laboratory of Eco-Environment-Related Polymer Materials of the Ministry of Education of China for their financial support for this work.
A one-pot three-component method for the synthesis of 2-methyl-3-aminobenzofurans using calcium carbide as a concise solid alkyne source,and salicylaldehydes and secondary amines as starting materials is described.Thi...
the National Natural Science Foundation of China (Nos.21971001,21702001);the Start-up Grant from Anhui University for financial support of this work。
A visible light and base promoted O-H insertion/cyclization of para-quinone methides with aryl diazoacetates is developed. This one-pot two step reaction offers a mild and efficient approach for the synthesis of biolo...
the National Natural Science Foundation of China(21702154,51773157);the Fundamental Research Funds for the Central Universities;the Opening Project of Key Laboratory of Materials Processing and Mold and Beijing National Laboratory for Molecular Sciences(BNLMS201905)。
Two p-type small molecules BDTT-TR and TBFT-TR with benzo[1,2-b′:4,5-b′]dithiophene(BDT)and thieno[2,3-f]benzofuran(TBF)as central core units are synthesized and used as donors in all-small-molecule organic solar ce...
financial support from the National Nature Science Foundation of China(Nos.81760625,81660576 and81560563);Projects of Guizhou Province(Nos.[2016]5623,JG[2016]06,[2019]1402,[2017]5609 and[2018]5781)。
A quinine-derived thiourea-catalyzed inter-/intramolecular Michael cycloaddition of chromoneoxindole/benzofuranone synthons with 3-substituted methylenebenzofuranones has been established,which constructed enantiomeri...
The authors appreciate the financial supports from the National Natural Science Foundation of China(Nos.81573292 and 81903463);Department of Education of Liaoning Province(2017LQN03);Department of Science and Technology of Liaoning Province(20180540032).
Summary of main observation and conclusion Benzofuran has antifungal activity as the inhibitor of N-myristoyltransferase.Twenty-nine novel benzofuran-semicarbazide hybrids were designed and synthesized by principle of...