蛤蟆油水溶性总蛋白对小鼠耐缺氧及抗氧化能力的影响  

Affect of Oviductus Ranae's water-miscible total proteins on anti-hypoxia and antioxidation capacity of mice

作　　者：吴运明[1] 赵雨[2] 王思明[2] 张鑫[2] 张惠[2] 

机构地区：[1]长春中医药大学体育部,长春130117 [2]长春中医药大学中医药与生物工程研发中心,长春130117

出　　处：《食品科技》2012年第4期47-50,共4页Food Science and Technology

基　　金：国家"十一五"科技支撑项目(2007BAI38B06)

摘　　要：目的:研究蛤蟆油水溶性总蛋白对小鼠耐缺氧和抗氧化能力的影响。方法:记录小鼠在常压耐缺氧、亚硝酸中毒、急性脑缺血性缺氧实验中的存活时间,测定过氧化损伤模型中小鼠肝脏和血清中丙二醛(MDA)含量和超氧化物歧化酶(SOD)活力的变化。结果:蛤蟆油水溶性总蛋白可明显地延长亚硝酸中毒、急型脑缺血性缺氧所致小鼠存活时间,对小鼠常压耐缺氧的存活时间无明显的影响。蛤蟆油水溶性总蛋白能显著降低肝脏和血液中丙二醛(MDA)含量,提高肝脏和血液中超氧化物歧化酶(SOD)的活力。结论:说明了蛤蟆油水溶性总蛋白具有耐缺氧和抗氧化的作用。Objective：Studied on the effect of Oviductus Ranae＇s water-miscible total proteins on anti-hypoxia and anti-oxidation capacity of mice.Methods：Observed mice in bearing hypoxia at normal pressure,nitrite poisoning,acute cerebral ischemic anaerobic surviving time.Measured liver and blood serum malonaldehyde（MDA） content,superoxide dismutase（SOD） activity of changes.Results：The water-miscible total proteins can obviously extend a sodium nitrite poisoning,acute cerebral ischemic anaerobic by mice survival time.At normal pressure mice survival time didn＇t have some influence.Oviductus Ranae＇s water-miscible total proteins can significantly reduce MDA,significantly increase activity of SOD.Conclusions：The result provided the Oviductus Ranae＇s water-miscible total proteins had hypoxia tolerance and antioxidant effect.

关 键 词：蛤蟆油 水溶性蛋白 耐缺氧 抗氧化 

分 类 号：TS201.21[轻工技术与工程—食品科学]