低磷奶牛红细胞抗氧化功能的研究  

Studies on the Anti oxidant Function of Erythrocytes in Hypophosphatemic Cows

作　　者：宣大蔚[1] 石发庆[1] 王伟[1] 徐世文[1] 邹风驰 李国江 殷培安 柏世江 陈少敏 

机构地区：[1]东北农业大学,黑龙江哈尔滨150030 [2]黑龙江省安达畜牧局,151400 [3]黑龙江省哈尔滨畜牧兽医技术服务中心,150016

出　　处：《中国兽医杂志》2000年第3期7-9,共3页Chinese Journal of Veterinary Medicine

基　　金：黑龙江省自然科学基金资助项目

摘　　要：利用自然病例 ,采取分组 (血尿组、低磷组、对照组 )对比的方法 ,对低磷奶牛红细胞超氧化物歧化酶 (SOD)、谷胱甘肽过氧化物酶 (GSH- Px)活性和丙二醛 (MDA)含量进行了测定。结果表明 ,低磷组及血尿组奶牛红细胞平均 SOD、GSH- Px活性明显低于对照组 ,而 MDA含量显著高于对照组 ;直线相关分析表明 ,血清磷含量与 SOD、GSH- Px活性呈极显著正相关 (相关系数及回归方程分别为 r=0 .94 1,r=0 .84 ;Y=4 81.50 X+1733.35,Y=2 9.93X+140 .4 7,P<0 .0 1) ,与 MDA含量呈极显著负相关 (r=- 0 .935,Y=- 1.0 2 X+8.4 1,P<0 .0 1)。结果证明 ,奶牛发生低磷酸盐血症和血红蛋白尿症时 ,红细胞抗氧化功能酶活性显著降低 ,过氧化产物显著增加 ,存在红细胞膜受自由基攻击的可能性 ;The anti oxidant function of erythrocytes in hypophosphatemic cows was studied.The cows were divided into three groups,including haemoglobinuria group(HNG),low phosphorus group(LPG)and healthy group(HG).The results showed that the anti oxidant function of erythrocytes in hypophosphatemic cows decreased significantly.Every index reflecting the anti oxidant functions of erythrocytes had significant differences among the three groups.There were a significant positive correlation between serum phosphorus and erythrocytic SOD activity and GSH Px activity,and a negative correlation between serum phosphorus and erythrocytic MDA content.

关 键 词：奶牛 磷 红细胞 抗氧化功能 血红蛋白尿症 溶血 

分 类 号：S858.236.6[农业科学—临床兽医学] S858.237.1[农业科学—兽医学]