TIA患者颈部血管病变的超声学研究  

Cervical arteries' ultrasonography in patients with transient ischemic attack

作　　者：吕达平[1] 何志超[2] 吴筠凡[2] 吴君霞[2] 李凯[2] 胡纪源[2] 韩咏竹[2] 

机构地区：[1]安徽医科大学第四附属医院,合肥230022 [2]安徽中医学院神经病学研究所附属医院,合肥230031

出　　处：《安徽医学》2012年第5期585-588,共4页Anhui Medical Journal

基　　金：安徽省卫生厅2009年青年科研基金资助(09B134)

摘　　要：目的通过颈部血管超声检测,探讨短暂性脑缺血发作患者的颈部动脉粥样硬化性病变及两者间的关系。方法通过检测73例TIA患者及71例同龄健康对照组的血管超声,进一步对TIA组加以分类:单纯TIA发作39例,合并各类脑梗死计34例,分析内膜厚度、管腔狭窄程度及斑块性质等参数,并加以比较。结果总体TIA组颈部动脉与对照组间各参数差异有统计学意义(P<0.05),其中,单纯TIA组与对照组比较,内膜厚度、管腔狭窄程度(P<0.05),但斑块性质差异无统计学意义(P>0.05);而合并脑梗死的TIA组与对照组间内膜厚度、管腔狭窄程度间差异有统计学意义(P<0.002),且斑块性质的差异有统计学意义(P<0.05),TIA患者两亚组间差异均无统计学意义(P>0.05)。结论血管超声对TIA患者的颈部动脉粥样硬化的改变具有重要的临床参考价值及指导意义,颈部血管动脉粥样硬化及由此导致血管狭窄是TIA重要的危险因素,且单纯TIA患者与已存在脑梗死的患者间,颈部脑血管的病理改变的性质及程度已相当,单纯TIA患者与脑梗死患者应受到同等重视。Objective To observe and analyze the atherosclerotic vasculopathy in patients with transient ischemic attack（TIA） and the relationship between them by studying uhrasonography of cervical arteries. Methods The results of cervical arteries＇ultrasonic examina- tion between 73 TIA patients（ simple TIA was 39 cases, TIA complicating with CI or LI was 34） were compared and analyzed. Seventy one health persons were classified in control group. Several atherosclerosis （AS） parameters such as intima - media thickness （IMT） , stenosis de- gree and the atherosclerotic plaques＇features were compared. Results Significant deviation existed in all parameters between the group of all TIA patients and control group, as well, as far as IMT and lumina stenosis degree were concerned, simple TIA subgroup had significant devi- ation to the control group, but there was no significant deviation about atherosclerotic plaque features between them; furthermore, between the two groups of TIA patients accompanied with CI and/or LI and the control, there was significant deviation in all parameters ; oppositely, there was short of significant difference between the two subgroups in TIA. Conclusion As to TIA patients, ultrasonic examination is a very important technique, whose value isnt inferior to that which is applied to CI and LI. AS and stenosis are substaintially risk factors to CI/LI but also J TIA, and about cervical arteries IMT and stenosis level and the plaques＇features, and both of them are to the same degree, so TIA should be equivalently thought highly to CI/LI by patients and physicians in clinical work.

关 键 词：短暂性脑缺血发作 动脉粥样硬化 血管超声 

分 类 号：R743.3[医药卫生—神经病学与精神病学]