玉蜀黍苞叶和玉米棒提取物α-糖苷酶抑制活性  

α-Glucosidase inhibitory activity of extracts from the bracts and bars of Zea mays L.

作　　者：尹震花[1] 顾雪竹[2] 顾海鹏[1] 康文艺[1] 

机构地区：[1]河南大学中药研究所,河南开封475004 [2]中国中医研究院中药研究所,北京100700

出　　处：《河南大学学报（医学版）》2012年第2期88-90,共3页Journal of Henan University:Medical Science

基　　金：河南省科技厅重点项目(102102310019)

摘　　要：目的评价玉蜀黍苞叶和玉米棒各提取物的α-葡萄糖苷酶抑制活性。方法通过建立体外α-葡萄糖苷酶抑制模型,对玉蜀黍苞叶和玉米棒各提取物进行活性筛选,并对提取物浓度与抑制活性关系进行研究。结果玉蜀黍苞叶和玉米棒乙酸乙酯部位抑制α-葡萄糖苷酶活性(IC50=275.5和233.5mg/L)均高于阳性对照阿卡波糖(IC50=1 103.1mg/L),且苞叶乙酸乙酯部位抑制活性低于玉米棒乙酸乙酯部位。结论玉蜀黍苞叶和玉米棒乙酸乙酯部位均有好的α-葡萄糖苷酶抑制活性。Objective To study the aglucosidase inhibitory activity of extracts from the bracts and bars of Zea mays L. Methods By establishing α-glucosidase inhibitory model in vitro, the activity of extracts from the bracts and bars of Z. mays L were screened. The relationship of inhibitory ratio and the extract concentration were also studied. Results The ethyl acetate extracts from the bracts and bars of Z. mays L had the higher inhibitor activity （IC50 275.5 and 233.5 mg/L） than that of acarbose （IC50=1 103.01 mg/L）, and the ethyl acetate extracts from bracts had lower inhibitor activity than the bars. Conclusion The ethyl acetate extracts from the bracts and bars of Z. mays L have good α-glucosidase inhibitory activity.

关 键 词：玉蜀黍 Α-葡萄糖苷酶 抑制活性 

分 类 号：R284.2[医药卫生—中药学]