饮食在肠易激综合征症状发作和治疗中的作用  

Role of food in onset of symptoms and treatment of irritable bowel syndrome

作　　者：王维达[1] 方秀才[1] 柯美云[1] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院消化内科,北京市100730

出　　处：《世界华人消化杂志》2012年第17期1531-1536,共6页World Chinese Journal of Digestology

基　　金：国家高科技研究发展计划(863计划)课题基金资助项目;No.2010AA023007;"十一五"国家科技支撑计划基金资助项目;No.2007BAI04B01~~

摘　　要：流行病学研究资料提示,肠易激综合征(irritable bowel syndrome,IBS)患者的症状发作与饮食有关.饮食影响IBS症状的机制仍未完全阐明,可能与食物的促动力和促胃肠激素分泌作用、食物不耐受、食物过敏和不良进食习惯等有关.有证据表明采用食物剔除和添加膳食纤维、益生菌和益生元等特殊食物成分的饮食调整治疗能缓解IBS的症状.本文从IBS与食物有关的表现、饮食影响IBS症状的原因和机制、饮食对IBS治疗的作用3个方面总结了相关研究的进展.Epidemiological studies have suggested that the onset of some symptoms in patients with irritable bowel syndrome（IBS） is related with food.Although the potential mechanisms are not fully elucidated,there is some evidence that the inherent prokinetic and crinogenic effects of food components,food intolerance and allergies,as well as poor eating habits could plausibly contribute to symptom onset.Food elimination,supplemental dietary f iber,and special additives such as probiotics and prebiotics could relieve IBS symptoms.In this article we will review current advances in understanding the relationship between food and onset of IBS symptoms,the possible mechanisms,and emerging therapeutics involving dietary administration.

关 键 词：肠易激综合征 饮食 食物不耐受 膳食纤维 益生菌 

分 类 号：R574[医药卫生—消化系统]