Concise synthesis of (-)-anisomycin  

作　　者：Ji Li Yan Hua Feng Xin Bai Li Wei Han Huan Qiu Liu Guo Guang Shao 

机构地区：[1]Department of Anesthesiology, The First Hospital of Jilin University, Changchun 130021,. China [2]Department of Thoracic Surgery, The First Hospital-of Jilin University, Changchun 130021, China

出　　处：《Chinese Chemical Letters》2012年第6期647-649,共3页中国化学快报（英文版）

基　　金：support from The First Hospital of Jilin University

摘　　要：The antibiotic （-）-anisomycin was synthesized starting from D-tyrosine using Sharpless asymmetric epoxidation as a key reaction followed by formation and hydrolysis of oxazoline set up all chiral center.The antibiotic （-）-anisomycin was synthesized starting from D-tyrosine using Sharpless asymmetric epoxidation as a key reaction followed by formation and hydrolysis of oxazoline set up all chiral center.

关 键 词：ANISOMYCIN D-Tyrosine Sharpless asymmetric epoxidation OXAZOLINE 

分 类 号：S573.904[农业科学—作物学] TQ464.4[化学工程—制药化工]