胃癌“无症可辨”的双向性队列研究及相关原因的logistic回归分析  

The Prospective Cohort Study and Logistic Regression Analysis of Correlative Reasons on No Symptoms for Analysis of Gastric Cancer

作　　者：王克穷[1] 于明洋[1] 孙立优 张振兴[1] 

机构地区：[1]陕西中医学院,陕西咸阳712000 [2]陕西省彩虹医院,陕西咸阳712000

出　　处：《中华中医药学刊》2012年第7期1527-1529,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：国家自然科学基金资助项目(30873471)

摘　　要：目的:探索胃癌在手术、化疗前后无证可辨与临床因素的相互关系,以期指导临床。方法:通过对2004年-2008年期间634次胃癌住院患者在手术、化疗前后病案的回顾性调查和466人1097次胃癌手术、化疗前后患者的前瞻性调查,其中前瞻性调查以胃癌无证可辨为因变量,以相关临床因素为自变量进行logistic回归分析。结果:在回顾性调查和前瞻性调查中无证可辨发病率分别为22.17%和16.77%;从logistic回归分析来看,呈正相关:外科切缘、化疗次数;呈副相关:年龄、卡氏评分、术前化疗前或化疗间歇期服用中药。结论:调查时段不同,无证可辨发病率,临床影响因素也不同。Objective：To explore the correlations between syndromeless differentiation and clinical factors on the pre-post-operation and chemotherapy of the gastric cancer,in order to guide the clinical practice.Methods：A retrospective study was performed on the case of gastric carcinoma patients in the hospital on 634 person-times pre-post-operation and chemotherapy from 2004 to 2008,and a prospective study was performed on 1097 person-times pre-post-operation and chemotherapy of 466 gastric carcinoma patients.The logistic regression analysis of the prospective study was carried out,taking ＇No symptoms for analysis＇ of the gastric cancer as the dependent variable respectively,and clinical factors as the independent variables,including the incidence of ＇no symptoms for analysis＇ in retrospective study.Results：The prospective rate was 22.17% and 16.77%,respectively.According to the logistic regression analysis,it was positive correlation with incisional edge and chemotherapy times,and was negative correlation with age,Karnofsky scores,taking Chinese traditional medicine pre-post-operation and and in chemotherapy interim.Conclusion：The incidence of ＇no symptoms for analysis＇ and clinical factors were varied with the different study periods.

关 键 词：胃癌手术 化疗前后 队列研究 无证可辨 LOGISTIC回归分析 

分 类 号：R735.2[医药卫生—肿瘤]