小麦戊聚糖润肠通便功能的实验研究  

Experimental Study on Wheat Araboxylan in Facilitating Bowel Movement

作　　者：黄觉非[1] 刘晋[2] 唐振闯[3] 孟斌[4] 吉琳琳[3] 郭长江[3] 

机构地区：[1]广西医科大学公共卫生学院,广西南宁530021 [2]中国人民解放军总后勤部军需装备研究所,北京100088 [3]军事医学科学院卫生学环境医学研究所,天津300050 [4]武警后勤学院,天津300162

出　　处：《食品研究与开发》2012年第8期20-22,31,共4页Food Research and Development

摘　　要：研究富含戊聚糖的小麦提取物的润肠通便作用,并探讨适宜剂量,为应用于功能食品提供依据。昆明小鼠分为低、中、高3个剂量组,另设空白对照与模型对照,以复方地芬诺酯建立便秘模型,通过计算墨汁推进率,判断受试样品对小鼠肠道蠕动功能的影响;通过测定首粒排红色粪便的时间和6 h内排便粒数及重量,判断受试样品对小鼠排便功能的影响,采用SPSS软件进行统计分析。3个剂量组的小麦戊聚糖提取物均可提高小肠墨汁推进率,与模型组相比具有显著差异;中、高剂量的小麦戊聚糖提取物可缩短首粒红便排出时间、提高6 h内排便数及重量,与模型组相比具有极显著差异。小麦戊聚糖提取物具有良好的促进排便和促进肠道蠕动功能,其中中剂量性价比最高,可推荐作为适宜的人体参考服用量。To investigate the effect of wheat extract rich in araboxylan on facilitating bowel movement and appropriate dosage for its application in functional food. The KM mices were divided into 3 groups：low dosage, moderate dosage and high dosage groups, normal control and model group were also set.The constipation model was developed with Compound Diphenoxylate Tablets, the ink pushing ratio was measured to judge the influence of the test sample on mice＇s intestinal peristalsis function,the defecating time of the first red shit, the number and weight of the shits that defecated in 6 hours were measured to judge the influence of the test sample on mice^s defecation function,and the data were analyzed by SPSS. Wheat Araboxylan Extract in three dosages all can promote small intestinal motility,the difference is significant ;and Wheat Araboxylan Extract in moderate and high dosage can shorten the defecating time of the first red shit and increase the weight and number of excreting faeces of mice, the difference is also significant. Wheat Araboxylan Extract is an ideal material for promotion facilitating bowel movement and defecating, the moderate dosage is possible the suitable dosage for hunman to refer to.

关 键 词：小麦提取物 戊聚糖 润肠通便 

分 类 号：R285.5[医药卫生—中药学]