胃内幽门螺杆菌感染与口腔挥发性硫化物关系的研究  

Relationship between H.pylori infection in stomach and volatile sulfur compounds in oral cavity

作　　者：孙立洲[1] 陈曦[2,3] 冯希平 

机构地区：[1]河北省唐山市协和医院口腔预防科,唐山063004 [2]上海交通大学医学院附属第九人民医院口腔预防儿童科 [3]上海市口腔医学重点实验室,上海200011

出　　处：《口腔医学》2012年第9期528-531,共4页Stomatology

基　　金：上海市重点学科建设项目(S30206);上海交通大学医学院科技基金项目(09XJ21026)

摘　　要：目的研究胃内幽门螺杆菌(H.pylori)感染者口腔挥发性硫化物的含量及组成与无细菌感染者之间的差异。方法对35名牙周健康的志愿者分别用GC-SCS检测口腔挥发性硫化物含量和14C呼气试验检测胃内H.pylori感染情况。结果胃内H.pylori阳性受试者口腔中二甲基硫[(CH3)2S]的含量和所占比例明显高于H.pylori阴性的受试者(P<0.05)。胃内H.pylori阳性受试者口腔中硫化氢(H2S)及甲硫醇(CH3SH)的含量与对照组无显著差异。结论提示口腔中(CH3)2S的比例过高可能与感染胃幽门螺杆菌有关。Objective To compare the contents and composition of volatile sulfur compounds in oral cavity between H. pylori positive subjects and healthy subjects. Methods The VSCs in thirty five periodontal healthy subjects were measured with GC-SCS and H. pylori in stomach was examined by 14C UBT. Results The study showed that the contents and proportions of dimethyl sulfide were signifi- cantly higher in H. pylori positive subjects than those in H. pylori negative ones （ P 〈 0. 05 ）. The contents of hydrogen sulfide and meth- yl mercaptan in H. pylori positive subjects were not significantly different with those in the control group. Conclusions The results of this study indicate that the high proportion of dimethyl sulfide in oral cavity might be related to H. pylori infection.

关 键 词：口臭 幽门螺杆菌 二甲基硫 

分 类 号：R781.9[医药卫生—口腔医学]