饮食中的脂肪酸对孕妇及其子代的作用研究进展  

A Review of the Effects of Dietary Fatty Acids on the Health of Pregnant Women and Offspring

作　　者：耿超宇[1] 庞广昌[1] 

机构地区：[1]天津市食品生物技术重点实验室,天津商业大学生物技术与食品科学学院,天津300134

出　　处：《食品科学》2012年第19期315-320,共6页Food Science

基　　金：国家自然科学基金项目(30871951);天津市科技支撑计划项目(10ZCKFNC01800)

摘　　要：妊娠期期间的饮食对母体和胎儿的健康都具有重要作用。脂肪酸作为人们日常饮食必不可少的成分,对人类健康的影响作用已日益凸显。孕妇脂肪酸的不科学摄入,不仅会损害自身健康,还对胎儿的发育,甚至其表观遗传产生不利影响。越来越多的研究证明,体内大量游离脂肪酸和ω-6脂肪酸会诱导炎症反应的发生,而ω-3脂肪酸的抗炎活性可以平衡体内的免疫状态。本文从脂肪酸体内代谢、免疫活性对妊娠期母体和胎儿的免疫状态、表观遗传方面的作用进行论述,为孕妇科学摄入脂肪酸提供指导意见。During the period of pregnancy which is very special in life, the diet is very important for maternal and fetal health. As an essential composition for daily diet, fatty acids have an effect on health, which has become increasingly prominent. Unscientific intake of fatty acids by pregnant women will not only damage their own health, but also have adverse influence on fetal development or even epigenetics. A growing number of studies have showed that the over-does free fatty acids and ω-6 fatty acids can induce the inflammatory response in vivo, while anti-inflammatory activity of ω-3 fatty acids can balance the response in vivo. The effect of fatty acids metabolism, immune activity on maternal and fetal immune status and epigenetics are discussed in this review. Advices about scientific intake of fatty acids for pregnant women are also provided at the end of this article.

关 键 词：脂肪酸 孕妇 胎儿 免疫 

分 类 号：R151.1[医药卫生—营养与食品卫生学] R151.4[医药卫生—公共卫生与预防医学]