γ-癸内酯的生物法制取  

Preparation of Gamma-Decalactone through Biological Pathway

作　　者：王勇志[1] 赵征[1] 曹小红[1] 

机构地区：[1]天津轻工业学院食品工程系,天津300222

出　　处：《食品与发酵工业》2000年第4期82-85,共4页Food and Fermentation Industries

摘　　要：γ 癸内酯 (GDL)是香料工业由生物技术得到的主要产品。采用生物技术可以通过生物合成、生物转化和生物催化得到GDL。生物合成法通过真菌和酵母在静止期能合成和积累对于细胞生长非必需的作为次生代谢产物的内酯 ;生物转化法以羟基脂肪酸、非羟基脂肪酸和脂肪酸酯底物 ,经过微生物体内酶转化成γ 羟基脂肪酸 ,然后转化成内酯 ;生物催化法是利用脂肪酶 (如EC3 1 1 3)催化脂肪的水解反应、酯化反应和酯交换反应 ,包括催化羟基脂肪酸形成内酯。Decalactone (GDL) is one of the most important products by biotechnology in flavouring industry. Producing GDL by biotechnology includes biosynthesis, biotransformation and biocatalysis. By biosynthesis fungus and yeasts synthesize and accumulate lactones, the secondary metabolites, in static phase. By biotransformation yeasts convert hydroxyl acids, non hydroxyl acids and its esters to γ hydroxyl acids ,the precursors of lactones,sequentially to lactones. By biocatalysis lipases such as EC 3.1.1.3 catalyze the hydrolysis reactions, esterification reactions and ester exchange reactions, including catalyzing hydroxyl acids to lactones.

关 键 词：Γ-癸内酯 生物合成 生物转化 生物催化 GDL 

分 类 号：TQ655[化学工程—精细化工]