Direct Asymmetric Michael Additions of Ketones to Nitroolefins and Chalcones Catalyzed by a Chiral C2-Symmetric Pyrrolidine-based Tetraamine  

作　　者：马世俊 吴璐璐 刘明 王永梅 

机构地区：[1]Department of Chemistry,The Key Laboratory of Elemento-Organic Chemistry,Nankai University,Tianjin 300071,China

出　　处：《Chinese Journal of Chemistry》2012年第11期2707-2713,共7页中国化学（英文版）

摘　　要：C2-Symmetric pyrrolidine-based tetraamine, available from commercially starting materials, showed good cata- lytic activity for asymmetric Michael additions of ketones to nitroalkenes especially to chalcones. The reactions proceeded to give the corresponding products in good yields and in a highly selective manner.C2-Symmetric pyrrolidine-based tetraamine, available from commercially starting materials, showed good cata- lytic activity for asymmetric Michael additions of ketones to nitroalkenes especially to chalcones. The reactions proceeded to give the corresponding products in good yields and in a highly selective manner.

关 键 词：asymmetric catalysis Michael addition tetraamine CHALCONES ENANTIOSELECTIVITY 

分 类 号：O624[理学—有机化学] Q965[理学—化学]