supported by the National Natural Science Foundation of China(22377064 and 21702114);CAMS Innovation Fund for Medical Sciences(CIFMS)(2021-12M-1-054);Youth Innovation Team Development Program of Shandong Higher Education Institutions(2022KJC004).
Comprehensive Summary Many industries are plagued by economic losses and product failures caused by counterfeit goods.Therefore,advanced anti-counterfeiting techniques are continuously needed.In this study,we construc...
supported by the National Council for Scientific Development-CNPQ/MCTI/FNDCT N18/2021,by the Concession of Research Funding Grant Number 406522/2021-9-1 to F.O.M.S.Abreu.Helcio Silva dos Santos acknowledges financial support from CNPq-PQ (Grant Number 306008/2022-0).
With the increase in antimicrobial resistance,it has become necessary to explore alternative approaches for combating and preventing diseases.DB-cinnamaldehyde(CNM)and Benzyl4-amino(B4AM)are bioactive compounds derive...
supported by the National Natural Science Foundation of China(21961045 and 22061048);Yunnan Provincial Key Laboratory Construction Plan Funding of Universities,the Reserve Talents of Young and Middle-aged Academic Leaders of Yunnan Province(202005AC160016);Yunnan Provincial Engineering Research Center Construction Plan Funding of Universities.
An efficient stereoselective cobalt-catalyzed hydrovinylative cyclization of 1,6-enynes with chalcones toobtain functionalized pyrrolidines has been developed. The products were furnished in good yields withup to 93% ...
financial support from the National Natural Science Foundation of China (Nos. 21802093, 21536003);Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi (No. 2019L0408);the Ph D Start-up Foundation of Shanxi Medical University (No. 03201501) for the financial support。
Several simple, fast and practical protocols have been developed to synthesize internal or terminal propargylamines and chalcones via A^(3)-coupling reaction of aldehydes, amines, and alkynes catalyzed by an easily av...
Homoisoflavonoids are in the subclass of the larger family of flavonoids having one more alkyl carbon than flavonoids. Among them, 8-C-Methylated homoisoflavones have not been extensively studied for synthesis and bio...
supported by ZheJiang Province Natural Science Funding of China (Nos. LQ18H280008, Y19B020043, and LY17H160059, China);the National Natural Science Foundation of China (No. 81803580, China);University Students in Zhejiang Science and Technology Innovation Projects (No. 2018R413004, China);National Undergraduate Training Programs for Innovation and Entrepreneurship (No. 201810343025, China);Granted by the Opening Project of Zhejiang Provincial Top Key Discipline of Pharmaceutical Sciences
Scavenging reactive oxygen species(ROS) by antioxidants is the important therapy to cerebral ischemia-reperfusion injury(CIRI) in stroke. The antioxidant with novel dual-antioxidant mechanism of directly scavenging RO...
Background: Chalcones are open-chain flavonoids which display a large number of pharmacological activities such as cytotoxic, anti-inflammatory including antioxidant. The objective of this study was to assess antioxid...
In the present study,synthetic chalcones,flavanones and Schiff bases were prepared starting from paraceamol,and evaluated their anticipated anti-inflammatory activity.Chalcones were synthesized by reacting 3-acetyl-4-...
supported by the Funds for the Xinjiang Key Research and Development Program(No.2016B03038-3);Personalized Medicines-Molecular Signature-based Drug Discovery and Development,Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDA12050301);West Light Foundation of the Chinese Academy of Science(No.XBBS201403)
The Vernohia anthelmintica L.'s extract is one of the most popular Uygur medicines used for vitiligo. It is believed that the chalcone compounds of the plant play an important role in the treatment since they may act...
Spurred by the alleged relevance of the thia-Michael reaction in the bioactivity of various classes of cinnam(o)yl natural products and by the development of a quick NMR assay to study this reaction, we have carried o...