CYSTEAMINE

作品数:23被引量:56H指数:5
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相关领域:农业科学更多>>
相关作者:张坤杨磊王筱冰王攀刘全宏更多>>
相关机构:东北师范大学陕西师范大学上海交通大学更多>>
相关期刊:《Asian pacific Journal of Reproduction》《Science Bulletin》《Bioactive Materials》《Journal of Animal Science and Biotechnology》更多>>
相关基金:国家自然科学基金广东省自然科学基金国家重点基础研究发展计划更多>>
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Combination of disulfiram and CopperCysteamine nanoparticles induces mitochondria damage and promotes apoptosis in endometrial cancer被引量:1
《Bioactive Materials》2024年第6期96-111,共16页Lijun Yang Cancan Yao Zhenning Su Yihao Fang Nil Kanatha Pandey Eric Amador Tian Diao Guo Bao Derong Cao Xihua Chen Xiangbo Xu Bin He Yufeng Zheng Wei Chen 
supported by the National Natural Science Foundation of China(22071066);CAMS Innovation Fund for Medical Science(CIFMS,No.2018-12M-1-004);the project from department of Education,Jiangsu Province for the School of CHIPS at XJTLU(EFP10120240023).
Endometrial cancer(EC)stands as one of the most prevalent gynecological malignancies affecting women,with its incidence and disease-related mortality steadily on the rise.Disulfiram(DSF),an FDA-approved medication pri...
关键词:COMBINATION DISULFIRAM Copper-Cysteamine nanoparticles Mitochondria damage Promotes apoptosis in Endometrial Cancer 
Copper-cysteamine nanoparticle-mediated microwave dynamic therapy improves cancer treatment with induction of ferroptosis被引量:5
《Bioactive Materials》2023年第6期322-330,共9页Hui Zhou Zhongtao Liu Zijian Zhang Nil Kanatha Pandey Eric Amador William Nguyen Lalit Chudal Li Xiong Wei Chen Yu Wen 
the support by the Natural Science Foundation of China(81773293,81873640,81970569,82000756);Natural Science Foundation of Hunan Province,No.2022JJ40700;the Key Project of Science and Technology Program of Hunan Provincial Science and Technology Department(2015GK3117,2017WK2063);the supports from Guangxi Jialouyuan Medical Inc.,Solgro;the distinguished award from UT Arlington as well as ROSFORCURE Inc.
Photodynamic Therapy(PDT)holds a great promise for cancer patients,however,due to the hypoxic characteristics of most solid tumors and the limited penetration depth of light in tissues,the extensive clinical applicati...
关键词:Cu-Cy MICROWAVE PDT Cell death Colorectal cancer Ferroptosis 
Maternal supply of cysteamine alleviates oxidative stress and enhances angiogenesis in porcine placenta被引量:7
《Journal of Animal Science and Biotechnology》2022年第1期181-196,共16页Shuangbo Huang Zifang Wu Zihao Huang Xiangyu Hao Longmiao Zhang Chengjun Hu Jianfu Wei Jinping Deng Chengquan Tan 
funded by Project of National Natural Science Foundation of China(No.31872985 and 31790411);Natural Science Foundation of Guangdong Province(No.2021A1515012116).
Background:Oxidative stress in placenta is associated with the occurrence of adverse pregnancy outcomes in sow,but there are few satisfactory treatment strategies for these conditions.This study investigated the poten...
关键词:ANGIOGENESIS CYSTEAMINE Oxidative stress PLACENTA SOW 
Study of copper-cysteamine based X-ray induced photodynamic therapy and its effects on cancer cell proliferation and migration in a clinical mimic setting被引量:9
《Bioactive Materials》2022年第1期504-514,共11页Xiangyu Chen Jiayi Liu Ya Li Nil Kanatha Pandey Taili Chen Lingyun Wang Eric Horacio Amador Weijun Chen Feiyue Liu Enhua Xiao Wei Chen 
This study was supported by by Clinical Research Center For Medical Imaging In Hunan Province(No.2020SK4001);the National Natural Science Foundation of China(Nos.22071065,81571784);Provincial Natural Science Foundation of Hunan(Nos.2019JJ40444,2019JJ40435);Scientific Research Project of Hunan Health and Family Planning Commission(No.B20180048).WC would like to thank the supports from Guangxi Jialouyuan Medical Inc.,Solgro,and the distinguished award from UT Arlington as well as the Pencis award.
Copper-cysteamine as a new generation of sensitizers can be activated by light,X-rays,microwaves,or ultrasound to produce reactive oxygen species.X-ray induced photodynamic therapy(X-PDT)has been studied extensively;h...
关键词:Copper-cysteamine Nanoparticle Photodynamic therapy X-RAY Cell migration Proliferation 
Challenges for cysteamine stabilization,quantification,and biological effects improvement
《Journal of Pharmaceutical Analysis》2020年第6期499-516,共18页Carla Atallah Catherine Charcosset Helene Greige-Gerges 
the Lebanese University and the“Agence Universitaire de la Francophonie,projet PCSI”for supporting the project(2018e2020).
The aminothiol cysteamine,derived from coenzyme A degradation in mammalian cells,presents several biological applications.However,the bitter taste and sickening odor,chemical instability,hygroscopicity,and poor pharma...
关键词:CYSTEAMINE Detection ENCAPSULATION SKIN Stability 
Use of copper-cysteamine nanoparticles to simultaneously enable radiotherapy,oxidative therapy and immunotherapy for melanoma treatment被引量:5
《Signal Transduction and Targeted Therapy》2020年第1期1852-1854,共3页Qi Zhang Xiangdong Guo Yingnan Cheng Lalit Chudal Nil Kanatha Pandey Jieyou Zhang Lun Ma Qing Xi Guangze Yang Ying Chen Xin Ran Chengzhi Wang Jingyi Zhao Yan Li Li Liu Zhi Yao Wei Chen Yuping Ran Rongxin Zhang 
supported by the National Natural Science Foundation of China through No.81872320,31600730,81602496,and 81272317;the Innovation and University Promotion Project of Guangdong Pharmaceutical University through No.2017KCXTD020.W.C.
Dear Editor,Melanoma,squamous cell carcinoma(SCC),and basal cell carcinoma(BCC)are three major types of skin cancer.Among them,melanoma is the most severe form and accounts for~4%of all newly diagnosed cancers annuall...
关键词:MELANOMA TREATMENT RADIOTHERAPY 
Compensation effects of coated cysteamine on meat quality, amino acid composition, fatty acid composition, mineral content in dorsal muscle and serum biochemical indices in finishing pigs offered reduced trace minerals diet被引量:8
《Science China(Life Sciences)》2019年第11期1550-1553,共4页Miaomiao Bai Hongnan Liu Kang Xu Xiaofeng Zhang Baichuan Deng Chengquan Tan Jinping Deng Pingping Bing Yulong Yin 
supported by the National Natural Science Foundation of China(31501964);the Youth Innovation Team Project of Institute of Subtropical Agriculture(ISA);China Academy Sciences(CAS)(2017QNCXTD_TBE);the China Agriculture Research System(CARS-35);the Natural Science Foundation of Guangdong Province(2017A030310410,2017A030310398);the National Natural Science Foundation of China(31790411)
Dear Editor.Trace mineral elements(ME)and amino acids have been demonstrated to be essential bioelements in animal nutrition.If there is a deficiency in ME,a number of biological functions in animals may be affected,i...
关键词:indices OXIDATIVE FINISHING 
Effect of melatonin and/or cysteamine on development and vitrification of buffalo embryos被引量:2
《Asian pacific Journal of Reproduction》2017年第4期176-180,共5页Mohamed MM El-Sokary Mohamed El-Raey Karima GhM Mahmoud Mahmoud EA Abou El-Roos Gamal MS Sosa 
Objective:To assess the effects of melatonin and/or cysteamineonin vitro maturation, culturing and post-warming of buffalo embryos.Methods: Buffalo oocytes were classified into control, cysteamine (50 μM), melatonin ...
关键词:MELATONIN CYSTEAMINE BUFFALO OOCYTE MATURATION VITRIFICATION 
Effect of using ascorbic acid and cysteamine supplementation onin-vitrodevelopment of buffalo embryos被引量:2
《Asian pacific Journal of Reproduction》2017年第2期85-88,共4页Al-shimaa Al-H.H.El-Naby Karima Gh.M.Mahmoud Gamal A.M.Sosa Mahmoud E.A.Abouel-Roos Youssef F.Ahmed 
Objective:To improvein vitro embryo production in buffalo by supplementation of L-ascorbic acid during maturation and development (experiment 1) and combination with another antioxidant as cysteamine (experiment 2).Me...
关键词:BUFFALO OOCYTES L-ascorbic ACID CYSTEAMINE EMBRYO DEVELOPMENT 
The reaction of cinnamaldehyde and cinnam(o)yl derivatives with thiols
《Acta Pharmaceutica Sinica B》2017年第4期523-526,共4页Alessandro Autelitano Alberto Minassi Alberto Pagani Orazio Taglialatela-Scafati Giovanni Appendino 
Spurred by the alleged relevance of the thia-Michael reaction in the bioactivity of various classes of cinnam(o)yl natural products and by the development of a quick NMR assay to study this reaction, we have carried o...
关键词:Cinnmaldeyde Michael addition ELECTROPHILES Conjugation CYSTEAMINE CHALCONES 
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