supported by the National Natural Science Foundation of China(22071066);CAMS Innovation Fund for Medical Science(CIFMS,No.2018-12M-1-004);the project from department of Education,Jiangsu Province for the School of CHIPS at XJTLU(EFP10120240023).
Endometrial cancer(EC)stands as one of the most prevalent gynecological malignancies affecting women,with its incidence and disease-related mortality steadily on the rise.Disulfiram(DSF),an FDA-approved medication pri...
the support by the Natural Science Foundation of China(81773293,81873640,81970569,82000756);Natural Science Foundation of Hunan Province,No.2022JJ40700;the Key Project of Science and Technology Program of Hunan Provincial Science and Technology Department(2015GK3117,2017WK2063);the supports from Guangxi Jialouyuan Medical Inc.,Solgro;the distinguished award from UT Arlington as well as ROSFORCURE Inc.
Photodynamic Therapy(PDT)holds a great promise for cancer patients,however,due to the hypoxic characteristics of most solid tumors and the limited penetration depth of light in tissues,the extensive clinical applicati...
funded by Project of National Natural Science Foundation of China(No.31872985 and 31790411);Natural Science Foundation of Guangdong Province(No.2021A1515012116).
Background:Oxidative stress in placenta is associated with the occurrence of adverse pregnancy outcomes in sow,but there are few satisfactory treatment strategies for these conditions.This study investigated the poten...
This study was supported by by Clinical Research Center For Medical Imaging In Hunan Province(No.2020SK4001);the National Natural Science Foundation of China(Nos.22071065,81571784);Provincial Natural Science Foundation of Hunan(Nos.2019JJ40444,2019JJ40435);Scientific Research Project of Hunan Health and Family Planning Commission(No.B20180048).WC would like to thank the supports from Guangxi Jialouyuan Medical Inc.,Solgro,and the distinguished award from UT Arlington as well as the Pencis award.
Copper-cysteamine as a new generation of sensitizers can be activated by light,X-rays,microwaves,or ultrasound to produce reactive oxygen species.X-ray induced photodynamic therapy(X-PDT)has been studied extensively;h...
the Lebanese University and the“Agence Universitaire de la Francophonie,projet PCSI”for supporting the project(2018e2020).
The aminothiol cysteamine,derived from coenzyme A degradation in mammalian cells,presents several biological applications.However,the bitter taste and sickening odor,chemical instability,hygroscopicity,and poor pharma...
supported by the National Natural Science Foundation of China through No.81872320,31600730,81602496,and 81272317;the Innovation and University Promotion Project of Guangdong Pharmaceutical University through No.2017KCXTD020.W.C.
Dear Editor,Melanoma,squamous cell carcinoma(SCC),and basal cell carcinoma(BCC)are three major types of skin cancer.Among them,melanoma is the most severe form and accounts for~4%of all newly diagnosed cancers annuall...
supported by the National Natural Science Foundation of China(31501964);the Youth Innovation Team Project of Institute of Subtropical Agriculture(ISA);China Academy Sciences(CAS)(2017QNCXTD_TBE);the China Agriculture Research System(CARS-35);the Natural Science Foundation of Guangdong Province(2017A030310410,2017A030310398);the National Natural Science Foundation of China(31790411)
Dear Editor.Trace mineral elements(ME)and amino acids have been demonstrated to be essential bioelements in animal nutrition.If there is a deficiency in ME,a number of biological functions in animals may be affected,i...
Objective:To assess the effects of melatonin and/or cysteamineonin vitro maturation, culturing and post-warming of buffalo embryos.Methods: Buffalo oocytes were classified into control, cysteamine (50 μM), melatonin ...
Objective:To improvein vitro embryo production in buffalo by supplementation of L-ascorbic acid during maturation and development (experiment 1) and combination with another antioxidant as cysteamine (experiment 2).Me...
Spurred by the alleged relevance of the thia-Michael reaction in the bioactivity of various classes of cinnam(o)yl natural products and by the development of a quick NMR assay to study this reaction, we have carried o...