云南省丽江纳西族儿童地中海贫血与G6PD缺乏症调查分析  

Epidemiological study on thalassemia and G6PD deficiency among the children of Naxi in Lijiang of Yunnan

作　　者：全星[1] 姚莉琴[1] 邹团标[1] 忽丽莎[1] 刘锦桃[1] 曹梅香 詹会莲 和玉琼 解丽钢 王兴田[1] 

机构地区：[1]云南省妇幼保健院,昆明650051 [2]丽江市妇幼保健院,674100

出　　处：《中国优生与遗传杂志》2013年第2期117-118,74,共3页Chinese Journal of Birth Health & Heredity

摘　　要：目的了解云南省丽江纳西族儿童地中海贫血和G6PD缺乏症的现状。方法 916名儿童进行地中海贫血检测:对调查者进行血细胞分析,PH8.6缓冲液醋酸纤维薄膜做电泳分析;G6PD缺乏症检测:采用改良葡萄糖6-磷酸脱氢酶(G6PD)测定比值法(手工操作法)进行检测。结果β-地贫检出率2.6%,α-地贫检出率2.6%,G6PD缺乏症检出率2.0%。结论云南省丽江纳西族儿童的地贫和G6PD缺乏症检出率低于云南3个边境州10个特有少数民族,可能与丽江不是疟疾流行区,人口流动多有关。该调查为云南省丽江纳西族进行遗传咨询及进行地贫和G6PD缺乏症的预防提供了有价值的基础资料。Objective： To investigate the carrier rate of thalassemia and G6PD deficiency among the children of Naxi in Lijiang of Yunnan.Method： 916 samples of children were verified by blood cell automatic analysis,hemoglobin electrophoresis,and erythrocyte glucose-6-Phosphate dehydrogenase deficiency（G6PD） diagnostic kit.Result： The incidence ofβ-thalassaemia was 2.6%,The incidence ofα-thalassaemia was 2.6%,The incidence of G6PD deficiency was 2.0%.Conclusion： Thalassemia and G6PD deficiency among the children of Naxi in Lijiang are Lower than 10 specific minority in three border states of Yunnan,there are related With it is not a malaria endemic area and population mobility in Lijiang.The investigation provides a valuable basis for information of thalassemia and G6PD deficiency prevention of Naxi in Lijiang of Yunnan.

关 键 词：儿童 地贫 G6PD缺乏症 流行病学 纳西族 云南 

分 类 号：R725.5[医药卫生—儿科]