代谢组学研究进展及其应用  

Advances in Metabonomics and Its Applications

作　　者：周秋香[1,2] 余晓斌[3] 涂国全[1] 王强[3] 胡文军[3] 李汉广[1,3] 

机构地区：[1]江西农业大学生物科学与工程学院,南昌330045 [2]江西农业大学附属医院,南昌330045 [3]江南大学生物工程学院,无锡204122

出　　处：《生物技术通报》2013年第1期49-55,共7页Biotechnology Bulletin

基　　金：国家自然科学基金项目(B060905);江苏省科技支撑项目(21176105)

摘　　要：代谢组学是系统生物学的重要组成部分,其通过研究生物体代谢物的变化来认识生命体的生理与生化状态,从而找出其中隐藏的规律。对代谢组学的含义,研究任务进行介绍;综述代谢组学的产生和技术平台及其在植物、微生物、疾病诊断及毒物学等领域的应用,并对代谢组学的发展趋势以及面临的挑战等问题进行评述。Metabonomics （ or metabolomics ） is an essential part of systems biology. Through the study of metabolic changes in organisms, their physiological and biochemical status can be known and the internal principle can be discovered. The meaning and research task of metabonomics were introduced in this paper. Generation, technological platform of metabonomics and its application in plants, microorganisms, disease diagnosis and toxicology were summarized. A review on the development trend and challenges were also given.

关 键 词：代谢组学 核磁共振 系统生物学 蛋白组学 数据分析 

分 类 号：Q591[生物学—生物化学]