Design and Synthesis of Polymeric Chiral Bicyclo[3.3.0] Diene as Reusable Ligand for Rhodium-Catalyzed Asymmetric 1,4-Addition  

作　　者：Hongyu Yang Minghua Xu 

机构地区：[1]Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China

出　　处：《Chinese Journal of Chemistry》2013年第1期119-122,共4页中国化学（英文版）

基　　金：Acknowledgement Financial support from the National Natural Science Foundation of China （Nos. 20632060, 20972172, 21021063）, and the Chinese Academy of Sciences is greatly acknowledged.

摘　　要：A series of A-B type sterically regular bicyclio[3.3.0] diene-based polymers were designed and synthesized as immobilized chiral diene ligands for asymmetric catalysis. With polymeric diene 6b, good to excellent enantiose- lectivities can be achieved in Rh-catalyzed asymmetric 1,4-addition of arylboronic acids to a,β-unsaturated ketones.A series of A-B type sterically regular bicyclio[3.3.0] diene-based polymers were designed and synthesized as immobilized chiral diene ligands for asymmetric catalysis. With polymeric diene 6b, good to excellent enantiose- lectivities can be achieved in Rh-catalyzed asymmetric 1,4-addition of arylboronic acids to a,β-unsaturated ketones.

关 键 词：asymmetric catalysis chiral ligand DIENE RHODIUM IMMOBILIZATION 

分 类 号：O621.34[理学—有机化学] O621.3[理学—化学]