新型抗抑郁药在儿童情绪障碍中的临床应用  

Clinical application of new type antidepressant drugs in emotional disorders of childrenhood

作　　者：刘均富[1] 黄英[1] 余瑞[1] 张小娟[1] 谭友果[1] 

机构地区：[1]自贡市精神卫生中心,四川自贡643000

出　　处：《四川医学》2013年第2期183-185,共3页Sichuan Medical Journal

摘　　要：目的比较新型抗抑郁药帕罗西汀、舍曲林、艾司西酞普兰在儿童情绪障碍中的应用。方法共纳入使用帕罗西汀、舍曲林、艾司西酞普兰的儿童情绪障碍患者60例,根据病历病情记录分别在治疗前及治疗第2、4、6周末采用临床疗效总评量表(CGI)评定临床疗效,用不良反应量表(TESS)评定不良反应。结果帕罗西汀组有效率为83.3%,舍曲林组有效率为88.9%,艾司西酞普兰组有效率为91.7%。总有效率为86.7%。不良反应发生率帕罗西汀组为20%,舍曲林组为22.2%,艾司西酞普兰为25%。结论新型抗抑郁药对儿童情绪障碍安全有效。Objective To compare the clinical usage of new type antidepressant drugs-paroxetine,sertraline,escitalopram in emotional disorders of Childrenhood.Methods 60 cases of emotional disorders of childrenhood were treated with paroxetine,sertraline,escitalopram were included in the study.The clinical efficacy of each patient was assessed with the Clinical Global Impression（CGI） before treatment and at treatment of 2,4,6 weekend.The side effects were recorded by using Treatment Emergent Symptom Scale（TESS）.Results The effective rate was 83.3% in the paroxetine group,the sertraline group was 88.9%,escitalopram effective rate was 91.7%.The total effective rate was 86.7%.The side effects of paroxetine group was 20%,the side effects of sertraline group was 22.2%,and the side effects of escitalopram was 25%.Conclusion The new type antidepressants drugs are safe and effective for emotional disorders of childrenhood.

关 键 词：新型抗抑郁药 儿童情绪障碍 

分 类 号：R749.4[医药卫生—神经病学与精神病学]