饮用绿茶对血管性认知功能障碍的影响  

Influence of drinking green tea on vascular cognitive impairment

作　　者：徐艳[1] 鞠洁旸[1] 杨英[1] 张磊[1] 訚亚涛[1] 施余露[1] 

机构地区：[1]武汉大学中南医院,湖北武汉430071

出　　处：《现代中西医结合杂志》2013年第10期1030-1031,1034,共3页Modern Journal of Integrated Traditional Chinese and Western Medicine

基　　金：湖北省自然科学基金资助项目(2010CHB02601)

摘　　要：目的探讨饮用绿茶的习惯对血管性认知功能障碍(VCI)及其影像学表现的影响。方法选择VCI患者77例,根据饮用的绿茶量分为A组(0杯或小于1杯/d)、B组(1～2杯/d)、C组(3～5杯/d及以上),对所有患者进行MMSE及MoCA评分,并依据脑MRI表现对脑白质损害程度及是否存在关键部位缺血进行评分。结果 VCI患者之间的血管危险因素无显著性差异(P>0.05),C组患者认知功能评分明显好于A组及B组(P均<0.05),各组患者之间的室周高信号(PVH)评分无显著性差异,而B组及C组患者的白质高信号(WM-HS)评分明显低于A组(P均<0.05),各组患者之间的关键部位病变无显著性差异。结论长期饮用绿茶的VCI患者,脑白质损害程度及认知功能障碍较轻。Objective It is to explore the effect of drinking green tea on vascular cognitive impairment （VCI）and MRI. Methods According to the frequency of green tea consumption, 77 participants with VCI were divided into A group （0 or 〈 1 cup/d） , B group （1 -2 cups/d） , C group （3- 5 cups/d or more）. All participants underwent neuropsychological tests including Mini Mental State Examination （MMSE） and Montreal Cognitive Assessment （MoCA）. The white matter lesions and strategic areas were visually assessed using MRI. Results The vascular risk factor among participants with various frequency of green tea consumption had no difference （ P 〉 O. 05 ）. The scores of cognitive function for those in group C were better than the ones in the other two groups （P 〈 0.05）. The periventricular hyperintensity （PVH） and strategic areas on MRI showed no significant difference among various groups （ P 〉 0.05）. But the white matter high signal （WMHS） on MRI for those with 1 - 2 cups/d or 3 - 5 cups/d green tea consumption less than those who consumed 0 or 〈 1 cup/d （ P 〈 0.05）. Conclusion The VCI participants with long - tern green tea consumption had mild lesion of cerebral white matter and better cognitive function.

关 键 词：绿茶 血管性认知功能障碍 白质 危险因素 磁共振成像 

分 类 号：R743[医药卫生—神经病学与精神病学]