血管性痴呆的智能测验与P_(300)的相关性  

The correlativity on intelligence test of dementia and P_(300) of vascular dementia

作　　者：张宗逸[1] 张杰伦[1] 陈鹏亚[1] 王威[1] 

机构地区：[1]黑龙江省哈尔滨市第一医院,150010

出　　处：《中国全科医学》2000年第4期264-265,共2页Chinese General Practice

摘　　要：目的　观察血管性痴呆患者的智能测验分与事件相关电位P30 0 潜伏期的相关性。方法　应用长谷川信彦痴呆量表测验血管性痴呆组 (2 7例 )和智能正常对照组 (33例 )两组患者智能。同时检测两组患者P30 0 潜伏期 ,并观察两组患者智能测验分与P30 0 潜伏期的相关性。结果　两组患者智能测验分有显著差异 (P <0 0 1) ,P30 0 潜伏期有显著差异 (P <0 0 1) ,智能测验分与P30 0 潜伏期呈明显负相关。结论　P30 0 潜伏期的延迟程度可反映血管性痴呆患者智能障碍的程度 ,是检查血管性痴呆的客观可靠指标。Objective To observe the interrelation between the score of intelligence test of patients with vascular dementia and Event-related potentials P 300 .Methods 27 patients as the study and 33 healthy controls were assessed by Hasegawa ,s Dementia Scale and detected by Latency of P 300 .In addition, we studied the interrelation between the score of intelligence test and Event-related potentials P 300 of two group patients.Results The score of intelligence test in vascular dementia was significantly higher than that of controls(P<0 01).The latency of P 300 in vascular dementia was obviously higher than that of controls(P<0 01).The score of intelligence test has significantly negative correlation to that of P 300 .Conclusion The delays in P 300 latency reflect the degree of vescular dementia and providea objective and reliable index of vascular dementia.

关 键 词：血管性痴呆 智能测验 事件相关电位P300 

分 类 号：R749.16[医药卫生—神经病学与精神病学]