Alzheimer′s病研究新进展  

The New Progression of Alzheimer′s Disease Research

作　　者：刘欣[1] 郗海涛[1] 刘玉琛[2] 

机构地区：[1]山东省济宁市第二人民医院,济宁272149 [2]济宁医学院附属医院,济宁272149

出　　处：《医学与社会》2000年第3期19-21,共3页Medicine and Society

摘　　要：对近年来国内外有关 AD的病因及发病机理、病理生化及防治等诸方面的研究新进展作一概述。AD的病因及发病机理大致可归纳为环境危险因素学说及遗传危险因素学说 ;病理生化研究方面的进展是 AD患者脑中有神经纤维缠结 (NFT)和老年斑 (SP) ,广泛而程度不一的脑萎缩及神经元和突触的缺失以及胆硷能活性降低对其记忆、认知障碍起着重要作用 ;防治研究方面的进展是基因工程研究的迅速进展。考虑到我国国情应当探讨和研究利用中药预防和治疗 AD。Summarize new progression that research AD′s cause of disease and pathogenesis and abroad recently pathologybiochemical and prevention and cure. cause of AD′s and pathogenesis were divided general two sort theory: environment dangerous factor theory and heredity dangerons factor theory; the new progression of pathologybiochemical research are the brain of AD′s patient contaius nerve fiber twineing (NFT) and senile plaque (SP). The brain atropry is extensive but atrophy degree isn′t equal. the nerve cell and synapse deficiency. the cholinergic activity reduce playing imjportant role about memory and cognitioe hiuder. The new progression of prevention and cure rerearch isvrapidly progression of gene engineering research. Consider to real circumstances of China, we should take advantage of traditional chinese medicine to provent and cure AD.\;

关 键 词：Alzheimer's 神经纤维缠结 老年斑 

分 类 号：R749.16[医药卫生—神经病学与精神病学]