supported by the National Clinical Research Center for Geriatrics of West China Hospital (Z2021LC001);the West China Hospital 1.3.5 Project for Disciplines of Excellence(ZYYC20009)。
Tau protein (encoded by the MAPT gene) is an attractive therapeutic target for the treatment of Alzheimer’s disease (AD) and other “tauopathies”, where aggregated tau pathology accumulates in neurons. Since tau dep...