精神分裂症患者内部动机与心理理论的相关性  

A correlation study of intrinsic motivation and theory of mind in schizophrenia

作　　者：李倩倩[1] 汪凯[1] Jimmy Choi 董毅[3] 朱春燕[1] 杨丽达[3] 刘勇[3] 赵子丛[1] 

机构地区：[1]安徽医科大学医学心理学系,合肥230022 [2]美国哥伦比亚大学医学中心 [3]安徽省精神卫生中心

出　　处：《中华行为医学与脑科学杂志》2013年第6期529-532,共4页Chinese Journal of Behavioral Medicine and Brain Science

基　　金：国家自然科学基金项目（81171273）;安徽省高校省级自然科学研究重点项目（KJ2010A165）

摘　　要：目的 探讨精神分裂症患者内部动机损害及其与心理理论缺陷之间的关系.方法 采用精神分裂症内部动机量表（IMI-SR）和心理理论故事图片任务（ToM-PST）对70例精神分裂症患者进行测试,与60例健康对照者作比较.结果 患者组IMI-SR总分[（88.43±22.42）分]、兴趣性因子分[（29.11±8.31）分]和选择性因子分[（29.71 ±8.82）分]均低于对照组[分别为（97.77±27.31）,（32.03±8.29）和（35.33±9.85）分,P＜0.05 ～0.01].患者组ToM-PST总分[（36.59±11.85）分]显著低于对照组[（57.17±2.08）分,P＜0.01],各因子分组间差异均具有统计学意义（均P＜0.01）.相关分析显示,IMI-SR总分与PANSS总分（r=-0.255,P＜0.05）、阴性症状分（r=-0.361,P＜0.01）和阳性症状分（r=-0.298,P＜0.05）呈负相关.患者组IMI-SR总分与ToM-PST总分（r=0.345,P＜0.01）、理解初级信念（r=0.296,P＜0.05）、理解初级错误信念（r=0.243,P＜0.05）、初级信念总分（r=0.311,P＜0.01）、理解次级错误信念（r=0.254,P＜0.05）、次级信念总分（r=0.284,P＜0.05）和理解欺骗（r=0.286,P＜0.05）呈正相关.控制症状评分后,患者组IMI-SR总分与ToM-PST总分及其理解初级信念分、初级信念总分、理解次级信念、次级信念总分和理解欺骗分的相关性仍具统计学意义.结论 精神分裂症患者存在内部动机和心理理论损害,患者内部动机障碍和心理理论缺陷可能具有某种共同的病理生理基础.Objective To explore intrinsic motivation and its relationship to theory of mind in patients with schizophrenia.Methods Seventy schizophrenic patients without treatment and sixty healthy subjects were assessed using the Intrinsic Motivation Inventory for Schizophrenia Research （IMI-SR） and the Theory-of-Mind Picture-Sequencing Task （ToM-PST）.Results Compared with healthy subjects,schizophrenic patients showed significantly less IMI-SR total score （97.77 ± 27.31 vs 88.43 ± 22.42,P 〈 0.01） and subscores of interest （32.03 ± 8.29 vs 29.11 ± 8.31,P 〈 0.05） and choice （35.33 ± 9.85 vs 29.71 ± 8.82,P 〈 0.01）.Schizophrenic patients also had significantly less total score （36.59 ± 11.85 vs 57.17 ± 2.08,P〈 0.01） and subscores of ToM-PST compared to normal controls （all P 〈 0.01）.Correlation analysis showed a negative correlation between IMI-SR total score and PANSS total score （r =-0.255,P 〈 0.05） and the subscores of negative （r =-0.361,P 〈 0.01）and positive （r =-0.298,P 〈 0.05） symptoms.There was significantly positive correlation between IMI-SR total score （r =0.345,P 〈0.01） and its subscores of the understanding of first order belief（r =0.296,P 〈 0.05）,the understanding of first order false belief（r =0.243,P 〈 0.05）,first order belief total points （r =0.311,P 〈 0.01）,the understanding of second order false belief（r =0.254,P 〈 0.05）,second order belief total points （r =0.284,P 〈 0.05）,and the understanding of intended deception（r =0.286,P 〈 0.05） in schizophrenic patients.After controlling for the PANSS total score,the correlation between IMI-SR total score and ToM-PST score and its subscores of the understanding of first order belief,first order belief total points,the understanding of second order belief,second order belief total points,the understanding of intended deception was remain significant.Conclusion Schizophrenic patients had impairments of intrinsic motivation and theory of mind,and intrinsic motivatio

关 键 词：精神分裂症 内部动机 心理理论 精神症状 

分 类 号：R749.3[医药卫生—神经病学与精神病学]