赤灵芝GL-2发酵液中多糖组分及活性研究  

Studies on separation and activity of GL-2 fermentative product

作　　者：孔乐生[1] 黄瑞珊[1] 罗九甫[1] 

机构地区：[1]上海交通大学生命科学技术学院,上海200030

出　　处：《工业微生物》2000年第3期27-30,共4页Industrial Microbiology

基　　金：上海汇成 (集团 )有限公司资助

摘　　要：对赤灵芝GL 2菌株发酵液中胞外多糖的提取进行了研究。通过乙醇分级沉淀对发酵液中多糖进行了分离 ,并采用凝胶柱层析法检测了各级份中多糖的分子量分布范围。动物实验证明 ,分级沉淀各级份均能促进小鼠体重增长 ,增强小鼠白细胞吞噬细菌的能力 ,提高红细胞中SOD酶的活力 ,其中 6 0Ganoderma lucidum (GL?2) fermentative product was precipitated by alcohol with different strength. When the strength of alcohol was denser, the output of polysaccharides was higher. Fractional precipitation could separate the water soluble Ganoderma polysaccharides to several constituents. The molecular weight range in each constituent was measured by gel filtration. Mice grew more rapidly after they had eaten polysaccharides extracted from GL?2 fermentative product. All the constituents showed stimulating effects on phagocyte function of leukocytes and enzyme activity of SOD in mice. And effects of the constituent with 60% were the most obvious among them.

关 键 词：赤灵芝 分级沉淀 胞外多糖 生物活性 发酵 

分 类 号：TQ92[轻工技术与工程—发酵工程]