室管膜下巨细胞型星形细胞瘤的临床分析  

Clinical analysis of subependymal giant cell astrocytoma

作　　者：杨斌[1] 曾现伟[1] 潘顺[1] 李瑜[1] 季泰令[1] 张波[1] 高明清[1] 

机构地区：[1]潍坊医学院附属医院神经外科,261031

出　　处：《中国微侵袭神经外科杂志》2013年第7期292-294,共3页Chinese Journal of Minimally Invasive Neurosurgery

基　　金：山东省科技攻关计划资助项目(编号:2011GFS11829)

摘　　要：目的探讨室管膜下巨细胞型星形细胞瘤（SEGA）的临床特点、影像学表现、治疗方法及预后。方法回顾性分析12例经病理证实的SEGA病人的临床资料，其中经胼胝体人路8例，经额叶皮质人路4例。结果肿瘤均获全切除；本组无围手术期并发症，无死亡病例；术后均未行放化疗。随访9～112个月，无肿瘤复发，平均KPS评分为85分。结论SEGA是一种少见的神经上皮良性肿瘤，多与结节性硬化综合征并发；易发生于男性儿童，以侧脑室多见，影像学表现具有相对特异性，肿瘤全切除后预后良好。Objective To study the clinical characteristic, radiological features, therapeutic method and prognosis of subependymal giant cell astrocytoma （SEGA）. Methods Clinical data of 12 patients with SEGA were analyzed retrospectively, who were operated on via transcallosal approach in 8 patients and frontal transcortical approach in 4. Results Total tumor removal was achieved in all the patients. There were no perioperative complications and no patients died. The radiotherapy and chemotherapy was not performed in any patient after surgery. During a follow-up period of 9 to 112 months, no patient suffered from recurrence, and the average Kamofsky Performance Scale score was 85. Conclusions SEGA is a rare benign neuroepithelial tumor and is inclined to accompany with tuberous sclerosis complex. SEGA usually occur in male children and lateral cerebral ventricle is a main predilection site. The neuroimaging results of SEGA are characteristic and total removal leads to a good prognosis.

关 键 词：星形细胞瘤 结节性硬化症 神经外科手术 

分 类 号：R739.41[医药卫生—肿瘤]