氨噻肟酸稀土配合物的合成、抗氧化性及抗菌活性的研究  

Synthesis, Antioxidative Activity and Antibacterial Activity of Complexes of Rare Earth with Syn-2- (2 ' - Aminothiazolyl - ) - 2 -Methoxyimino Acetic Acid

作　　者：王敏[1] 李一志[1] 李勤喜[1] 王流芳[1] 

机构地区：[1]兰州大学化学系,兰州730000

出　　处：《无机化学学报》2000年第5期710-714,共5页Chinese Journal of Inorganic Chemistry

基　　金：国家科委生命科学技术发展中心资助!(No.96-901-05-128);新药研究国家重点实验室基金

摘　　要：合成 了 １２种稀土氨噻肟酸（ＨＬ）固体配合物，其通式为 ＲＥＬ３（ＲＥ＝ Ｌａ， Ｃｅ， Ｐｒ， Ｎｄ， Ｓｍ， Ｅｕ， Ｇｄ， Ｔｂ， Ｅｒ， Ｔｍ，Ｙｂ，Ｙ）。利用元素分析、红外光谱、核磁共振氢谱、摩尔电导、热分析等测试手段对配合物进行了表征，研究了ＮｄＬ３、ＥｒＬ３配合物在 ＤＭＳＯ溶液中电子吸收光谱，计算了电子云伸展效应参数β，共价参数δ和键合参数 ｂ１／２，讨论了配合物的共价成键情况，并对其抗氧化及抗菌活性做了研究。New twelve complexes of rare earth with syn-2- (2'-aminothiazolyl-) -2-methoxyimino acetic acid (HL) have been prepared and characterized by elemental analyses, IR, molar conductance, TG-DTA and 1H NMR spectra. These complexes have the general formula REL3 (RE = La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Er, Tm, Yb, Y). IR spectra indicate that the bidentate coordination mode of carboxylate ions to rare earth ion in REL3 compounds. The electronic spectra of Nd3 + and Er3 + have been studied and the spectral parameters have been calculated and discussed. The antioxidative activity and antibacterial activity have been studied.

关 键 词：稀土配合物 氨噻肟酸 抗氧化性 抗菌活性 合成 

分 类 号：O614.33[理学—无机化学]