桥本氏病与非桥本氏病合并甲状腺癌的临床比较  

Hashimoto's disease combined thyroid cancer compared with non-Hashimoto's disease combined thyroid cancer

作　　者：张志鹏[1] 周娜[1] 黄鹏[1] 廖辉军[1] 孔繁晶[1] 常实[1] 

机构地区：[1]中南大学湘雅医院普通外科,长沙410008

出　　处：《中国肿瘤临床与康复》2013年第8期801-804,共4页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的比较桥本氏病(HD)合并甲状腺癌与非桥本氏病合并甲状腺癌的临床特点。方法中南大学湘雅医院于2002年1月至2011年7月间共手术治疗桥本氏病66例,经术后石蜡病检证实为桥本氏病合并甲状腺癌者41例,回顾性分析这41例桥本氏病合并甲状腺癌与同期随机抽选的30例非桥本氏病合并甲状腺癌的临床资料,并进行统计学分析。结果桥本氏病合并甲状腺癌与非桥本氏病合并甲状腺癌在性别、发病年龄、血清自身免疫抗体的比较上差异均有统计学意义(P<0.05)。结论与非桥本氏病合并甲状腺癌相比,桥本氏病合并甲状腺癌多见于女性患者,发病年龄早,常伴有血清自身免疫抗体的升高,因此临床上应重视桥本氏病患者的长期随访,在此期间若高度怀疑有癌变,应及时手术治疗。Objective To compare the clinical features of Hashimoto＇s diseases combined thyroid cancer with non-Hashimoto＇s diseases combined thyroid cancer.Methods 66 cases Hashimoto＇s disease were treated surgically between January 2002 and July 2011 in XiangYa Hospital,Central South University,including 41 cases Hashimoto＇s disease combined thyroid cancer,which were confirmed by paraffin pathological examination after surgery.To review retrospectively and analyze statistically the clinical data about 41 cases Hashimoto＇s disease combined thyroid cancer and 30 cases non-Hashimoto＇s disease combined thyroid cancer selected randomly in the same time.Results Statistical differences（P 0.05） were performanced in gender,age,serum autoimmune antibodies.Conclusions Compared with non-Hashimoto＇s disease combined thyroid cancer,Hashimoto＇s disease combined thyroid cancer patients were more common in female,early age,high serum autoimmune antibodies,therefore,long follow-up were paid more attention to Hashimoto＇s disease patients,and if suspect highly canceration,surgical treatment must be taken actively in time.

关 键 词：桥本氏病 甲状腺癌 诊断 治疗 

分 类 号：R736.1[医药卫生—肿瘤]