高强度超声破坏兔肝肿瘤营养血管的彩色多普勒能量图和病理观察  

The Damage Effect of High Intensity Ultrasound on the Rabbit Liver Carcinoma Vascularities Observed with Color Doppler Energy and Pathology

作　　者：关利铭[1] 冉海涛[2] 伍烽[1] 白晋[1] 李艳 李崇雁[1] 杜永洪[1] 王智彪[1] 

机构地区：[1]重庆医科大学超声医学工程研究所,400016 [2]重庆医科大学附二院超声科,400016

出　　处：《中国超声医学杂志》2000年第11期801-804,共4页Chinese Journal of Ultrasound in Medicine

基　　金：国家九五重点科技攻关项目!(96- 90 5- 0 2 - 0 1 );国家自然科学基金项目!(39770 841 )

摘　　要：目的 :观察高强度超声 ( HIU)对肿瘤营养血管的破坏作用。方法 :采用二维灰阶、彩色多普勒能量图和病理结合的方法 ,观察 HIU对兔 VX2 肝脏肿瘤营养血管破坏的情况。结果 :HIU治疗后 ,肿瘤组织回声增强 ,彩色多普勒能量图显示肿瘤组织内部血管影明显减少或消失 ,病理学检查方法显示肿瘤营养血管和肿瘤组织凝固性坏死。结论 :HIU可能较完全破坏肿瘤营养血管 ,从而有可能抑制肿瘤的再生和转移 ,促使肿瘤良性化。Objective:To evaluate the damage effect of high intensity ulstrasound(HIU)for carcinomatic vascularities.The effect is important for HIU to inhibitit tumor growth,metastases and transfer it into benign state.Methods:The animal models of the VX 2 tumor in the rabbit liver were set up,and histological examination combined with grey scale ultrasonography and the color Doppler energy was observed.Results:After HIU treatment,the ultrasonography echo intensity of tumor tissue was increased,while the imaging of carcnoma vascularities with the tumor were decreased or dismissed.Histological examination indicated that HIU made carcinoma vascularities within the whole tumor tissue coagulative necrosis.Conclusions:HIU may damage carcinoma vascularities thoroughly,in such away it may inhibit tumor growth and metastases,that makes tumor return benign form.

关 键 词：高强度超声 彩色多普勒能量图 肝肿瘤 病理 

分 类 号：R735.7[医药卫生—肿瘤]